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Giants vs. Lions prediction: Detroit favored to win in NFL Week 12, 2025
Get New York Giants vs Detroit Lions predictions for NFL Sunday.

The Detroit Lions and New York Giants will meet in Week 12 of the NFL season at Ford Field on Sunday, with kickoff at 1:00PM ET.
Based on the latest simulation results, Dimers' advanced NFL model predicts the Lions as the most likely winner of the Giants vs. Lions game.
This article offers an expanded analysis of Sunday's matchup, including projected touchdown scorers, best bets and player prop picks.
Giants vs. Lions prediction: Who will win and cover?
Since our Giants-Lions predictions earlier in the week, we have simulated the outcome of Sunday's NFL game between the Giants and Lions 10,000 times as part of our NFL predictions coverage.
Our leading predictive model currently gives the Lions an 88% chance of beating the Giants in Week 12 of the NFL season. Our predicted final score has the Lions winning 32-18.
According to our model, the Giants (+14.5) have a 53% chance of covering the spread, while the 50.5-point over/under has an equal 50-50 chance of hitting.
To see win probabilities for every matchup this week, check out our expert NFL Week 12 straight up picks.
Giants vs. Lions odds
We have sourced the best NFL odds in America for this game, which are listed here:
| Bet Type | Giants | Lions |
|---|---|---|
| Spread | +14.5 (-115) | -14.5 (+100) |
| Moneyline | +750 | -1100 |
| Total | o50.5 (-114) | u50.5 (+100) |
All odds are correct at the time of publication and are subject to change.
Giants vs. Lions picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Giants +14.5 | -115 |
| Moneyline | Giants | +750 |
| Total | Under 50.5 | +100 |
According to our NFL best bets, the top play to make on this game is Giants to win.
Giants vs. Lions TD scorers
Who will score a touchdown in Giants vs. Lions?
According to our list of touchdown scorer predictions for Week 12, Jahmyr Gibbs is most likely to score an anytime touchdown in Giants vs. Lions.
Our projections give Gibbs a 69.5% chance of scoring a TD at Ford Field, while the running back is an 18.9% chance of registering the first touchdown the game.
Anytime touchdown scorer predictions
New York Giants
| Player | Anytime TD Probability |
|---|---|
| Devin Singletary (RB) | 35.6% |
| Wan'Dale Robinson (WR) | 26.4% |
| Theo Johnson (TE) | 25.2% |
| Tyrone Tracy (RB) | 24.7% |
| Darius Slayton (WR) | 19.0% |
Detroit Lions
| Player | Anytime TD Probability |
|---|---|
| Jahmyr Gibbs (RB) | 69.5% |
| Amon-Ra St. Brown (WR) | 50.4% |
| David Montgomery (RB) | 49.2% |
| Jameson Williams (WR) | 37.5% |
| Brock Wright (TE) | 26.7% |
First touchdown scorer predictions
New York Giants
| Player | First TD Probability |
|---|---|
| Devin Singletary (RB) | 7.2% |
| Wan'Dale Robinson (WR) | 5.0% |
| Theo Johnson (TE) | 4.7% |
| Tyrone Tracy (RB) | 4.6% |
| Darius Slayton (WR) | 3.4% |
Detroit Lions
| Player | First TD Probability |
|---|---|
| Jahmyr Gibbs (RB) | 18.9% |
| Amon-Ra St. Brown (WR) | 11.1% |
| David Montgomery (RB) | 10.8% |
| Jameson Williams (WR) | 7.5% |
| Brock Wright (TE) | 4.9% |
Giants vs Lions player props
Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Giants and Lions. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 12 games.
Quarterbacks
Of the starting quarterbacks, the Giants' Jameis Winston is projected for 230 passing yards, while the Lions' Jared Goff is expected to throw for 252 yards.
| Player | Proj. Pass Yards |
|---|---|
| Jameis Winston (NYG) | 230 |
| Jared Goff (DET) | 252 |
Giants rushing
| Player | Proj. Rush Yards |
|---|---|
| Tyrone Tracy | 48 |
| Devin Singletary | 31 |
| Jameis Winston | 12 |
Lions rushing
| Player | Proj. Rush Yards |
|---|---|
| Jahmyr Gibbs | 81 |
| David Montgomery | 56 |
| Jared Goff | 3 |
Giants receiving
| Player | Proj. Rec. Yards |
|---|---|
| Wan'Dale Robinson | 59 |
| Darius Slayton | 45 |
| Theo Johnson | 39 |
| Isaiah Hodgins | 25 |
| Tyrone Tracy | 18 |
Lions receiving
| Player | Proj. Rec. Yards |
|---|---|
| Amon-Ra St. Brown | 86 |
| Jameson Williams | 66 |
| Jahmyr Gibbs | 32 |
| Brock Wright | 26 |
| Kalif Raymond | 19 |
Giants vs. Lions game-day updates and essential details
The NFL Week 12 matchup between the Lions and Giants at Ford Field is scheduled to commence at 1:00PM ET.
- Who: New York Giants vs. Detroit Lions
- Date: Sunday, November 23, 2025
- Time: 1:00PM ET/10:00AM PT
- Venue: Ford Field
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Conclusion
We predict the Lions, with an 88% win probability, will likely beat the Giants in Week 12 of the NFL season.
AI and automation have enhanced this article to quickly deliver accurate Giants vs. Lions insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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