Loading...

Giants vs. Lions prediction: Detroit favored to win in NFL Week 12, 2025

profile-img
Written by Jason Bevilacqua

Get New York Giants vs Detroit Lions predictions for NFL Sunday.

New York Giants-Detroit Lions Predictions and Game Preview.
New York Giants vs. Detroit Lions NFL prediction for Sunday, November 23, 2025.

The Detroit Lions and New York Giants will meet in Week 12 of the NFL season at Ford Field on Sunday, with kickoff at 1:00PM ET.

Based on the latest simulation results, Dimers' advanced NFL model predicts the Lions as the most likely winner of the Giants vs. Lions game.

This article offers an expanded analysis of Sunday's matchup, including projected touchdown scorers, best bets and player prop picks.

Giants vs. Lions prediction: Who will win and cover?

Since our Giants-Lions predictions earlier in the week, we have simulated the outcome of Sunday's NFL game between the Giants and Lions 10,000 times as part of our NFL predictions coverage.

Our leading predictive model currently gives the Lions an 88% chance of beating the Giants in Week 12 of the NFL season. Our predicted final score has the Lions winning 32-18.

According to our model, the Giants (+14.5) have a 53% chance of covering the spread, while the 50.5-point over/under has an equal 50-50 chance of hitting.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 12 straight up picks.

Giants vs. Lions odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type Giants Lions
Spread +14.5 (-115) -14.5 (+100)
Moneyline +750 -1100
Total o50.5 (-114) u50.5 (+100)

All odds are correct at the time of publication and are subject to change.

Giants vs. Lions picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Giants +14.5 -115
Moneyline Giants +750
Total Under 50.5 +100

According to our NFL best bets, the top play to make on this game is Giants to win.

 

Giants vs. Lions TD scorers

Who will score a touchdown in Giants vs. Lions?

According to our list of touchdown scorer predictions for Week 12, Jahmyr Gibbs is most likely to score an anytime touchdown in Giants vs. Lions.

Our projections give Gibbs a 69.5% chance of scoring a TD at Ford Field, while the running back is an 18.9% chance of registering the first touchdown the game.

Anytime touchdown scorer predictions

New York Giants

Player Anytime TD Probability
Devin Singletary (RB) 35.6%
Wan'Dale Robinson (WR) 26.4%
Theo Johnson (TE) 25.2%
Tyrone Tracy (RB) 24.7%
Darius Slayton (WR) 19.0%

Detroit Lions

Player Anytime TD Probability
Jahmyr Gibbs (RB) 69.5%
Amon-Ra St. Brown (WR) 50.4%
David Montgomery (RB) 49.2%
Jameson Williams (WR) 37.5%
Brock Wright (TE) 26.7%

First touchdown scorer predictions

New York Giants

Player First TD Probability
Devin Singletary (RB) 7.2%
Wan'Dale Robinson (WR) 5.0%
Theo Johnson (TE) 4.7%
Tyrone Tracy (RB) 4.6%
Darius Slayton (WR) 3.4%

Detroit Lions

Player First TD Probability
Jahmyr Gibbs (RB) 18.9%
Amon-Ra St. Brown (WR) 11.1%
David Montgomery (RB) 10.8%
Jameson Williams (WR) 7.5%
Brock Wright (TE) 4.9%

Giants vs Lions player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Giants and Lions. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 12 games.

Quarterbacks

Of the starting quarterbacks, the Giants' Jameis Winston is projected for 230 passing yards, while the Lions' Jared Goff is expected to throw for 252 yards.

Player Proj. Pass Yards
Jameis Winston (NYG) 230
Jared Goff (DET) 252

Giants rushing

Player Proj. Rush Yards
Tyrone Tracy 48
Devin Singletary 31
Jameis Winston 12

Lions rushing

Player Proj. Rush Yards
Jahmyr Gibbs 81
David Montgomery 56
Jared Goff 3

Giants receiving

Player Proj. Rec. Yards
Wan'Dale Robinson 59
Darius Slayton 45
Theo Johnson 39
Isaiah Hodgins 25
Tyrone Tracy 18

Lions receiving

Player Proj. Rec. Yards
Amon-Ra St. Brown 86
Jameson Williams 66
Jahmyr Gibbs 32
Brock Wright 26
Kalif Raymond 19

Giants vs. Lions game-day updates and essential details

The NFL Week 12 matchup between the Lions and Giants at Ford Field is scheduled to commence at 1:00PM ET.

NFL Week 12 betting promos and codes

Make the most of Dimers' Giants vs. Lions predictions by exploring the two exciting offers below.

DraftKings Sportsbook

Sign up for DraftKings Sportsbook! Bet $5, get $200 in bonus bets instantly plus over $200 off NFL Sunday Ticket.


Bet365 Sportsbook

Join Bet365 Sportsbook! Bet $5, get $200 in bonus bets win or lose.


Sports betting deal available for Missouri sports fans

To make the most of the upcoming Missouri launch, check out details on the latest Bet365 bonus code "DIMERS" that scores you $365 in bonus bets from a $10 bet — win or lose. Don't miss out!

Conclusion

We predict the Lions, with an 88% win probability, will likely beat the Giants in Week 12 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Giants vs. Lions insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

profile-img
Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

Advertiser disclosure

Related Articles

More Articles
Loading...
...
Read Article
...
Read Article
...
Read Article

Best Sportsbook Promotions

Why Join Multiple Sportsbooks?
Loading...