NBA picks today: Thanksgiving best bets include Spurs vs. Trail Blazers play [11/26/2025]

Today’s NBA picks for Thanksgiving are here, with Spurs vs. Trail Blazers among the top plays identified by our model across Wednesday’s NBA schedule.

Dimers’ predictive analytics engine runs 24/7, going over the latest basketball odds to find genuine betting edges. The result? Data-backed plays that help Dimers Pro members make smarter decisions.

List of NBA picks tonight [11/26, updated 11:46AM ET]

Below, you’ll find today’s best basketball bets, ranked by edge for Wednesday, November 26, 2025.

Spurs vs. Trail Blazers under 239.5 points (-105)

• Edge: 3.0%
• Probability: 54.2%
• Matchup: Spurs vs. Trail Blazers (10:00PM ET, Wednesday)

Our model has identified value on under 239.5 points in Spurs vs. Trail Blazers at -105 odds. A 54.2% probability produces an edge of 3.0%, making this the strongest play for today's NBA slate.

Trail Blazers ML (-112)

• Edge: 2.4%
• Probability: 55.2%
• Matchup: Spurs vs. Trail Blazers (10:00PM ET, Wednesday)

Trail Blazers ML carries a 2.4% edge and a probability of 55.2% at -112 odds, according to our model.

NBA best bets summary: Wednesday, 11/26/2025

As of 11:46AM ET, here are our top NBA bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Spurs vs. Trail Blazers	Under 239.5 Points	-105 @ BetMGM	3.0%	54.2%
Spurs vs. Trail Blazers	Trail Blazers ML	-112 @ FanDuel	2.4%	55.2%

List of upcoming NBA games to bet on [11/26/2025]

• Rockets vs. Warriors (10:00PM ET, Wednesday)
• Spurs vs. Trail Blazers (10:00PM ET, Wednesday)
• Suns vs. Kings (10:00PM ET, Wednesday)

Conclusion

Our NBA best bets are locked and loaded for November 26, 2025, featuring plays such as under 239.5 points in the Spurs vs. Trail Blazers matchup and Trail Blazers ML. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate NBA insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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