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MLB picks today: Saturday's MLB best bets include Athletics vs. Rangers play [4/25/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get MLB picks today and best bets for Saturday, April 25, 2026.
Today’s MLB picks for April 25, 2026 are here, with Athletics vs. Rangers and Padres vs. Diamondbacks among the top plays identified by our model across Saturday’s MLB slate.
Dimers’ predictive analytics engine runs 24/7, searching the latest baseball odds to uncover genuine betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of MLB best bets today [4/25, updated 8:03AM ET]
Below, you’ll find today’s best baseball bets, ranked by edge for Saturday, April 25, 2026.
Athletics vs. Rangers over 7.5 runs (-115)
- Edge: 6.8%
- Probability: 60.3%
- Matchup: Athletics vs. Rangers (7:05PM ET, Saturday)
Our model has identified value on over 7.5 runs in Athletics vs. Rangers at -115 odds. A 60.3% probability produces an edge of 6.8%, making this the strongest play for today's MLB slate.
Padres vs. Diamondbacks under 15.5 runs (-102)
- Edge: 6.2%
- Probability: 56.7%
- Matchup: Padres vs. Diamondbacks (6:05PM ET, Saturday)
Padres vs. Diamondbacks under 15.5 runs carries a 6.2% edge and a probability of 56.7% at -102 odds, according to our model.
Yankees vs. Astros over 9 runs (-102)
- Edge: 3.4%
- Probability: 53.9%
- Matchup: Yankees vs. Astros (7:10PM ET, Saturday)
Yankees vs. Astros over 9 runs at -102 odds shows a 3.4% edge, supported by a 53.9% probability in simulations.
Royals -1.5 (+140)
- Edge: 2.6%
- Probability: 44.3%
- Matchup: Angels vs. Royals (7:10PM ET, Saturday)
A 2.6% edge and 44.3% probability make Royals -1.5 vs. Angels at a value play in the Angels vs. Royals matchup, per our model.
Red Sox vs. Orioles over 7.5 runs (-105)
- Edge: 2.1%
- Probability: 53.3%
- Matchup: Red Sox vs. Orioles (12:05PM ET, Saturday)
Red Sox vs. Orioles over 7.5 runs at -105 odds presents a 2.1% edge, with simulations resulting in a probability of 53.3%.
MLB best bets summary: Saturday, 4/25/2026
As of 8:03AM ET, here are our top MLB bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Probability |
|---|---|---|---|---|
| Athletics vs. Rangers | Over 7.5 Runs | -115 @ BetMGM | 6.8% | 60.3% |
| Padres vs. Diamondbacks | Under 15.5 Runs | -102 @ FanDuel | 6.2% | 56.7% |
| Yankees vs. Astros | Over 9 Runs | -102 @ DraftKings | 3.4% | 53.9% |
| Angels vs. Royals | Royals -1.5 | +140 @ BetMGM | 2.6% | 44.3% |
| Red Sox vs. Orioles | Over 7.5 Runs | -105 @ DraftKings | 2.1% | 53.3% |
List of upcoming MLB games to bet on [4/25/2026]
- Red Sox vs. Orioles (12:05PM ET, Saturday)
- Mariners vs. Cardinals (2:15PM ET, Saturday)
- Guardians vs. Blue Jays (3:07PM ET, Saturday)
- Marlins vs. Giants (4:05PM ET, Saturday)
- Twins vs. Rays (4:10PM ET, Saturday)
- Nationals vs. White Sox (4:10PM ET, Saturday)
- Rockies vs. Mets (4:10PM ET, Saturday)
- Padres vs. D-Backs (6:05PM ET, Saturday)
- Athletics vs. Rangers (7:05PM ET, Saturday)
- Angels vs. Royals (7:10PM ET, Saturday)
- Yankees vs. Astros (7:10PM ET, Saturday)
- Pirates vs. Brewers (7:10PM ET, Saturday)
- Phillies vs. Braves (7:15PM ET, Saturday)
- Cubs vs. Dodgers (7:15PM ET, Saturday)
- Tigers vs. Reds (7:15PM ET, Saturday)
Conclusion
Our MLB best bets are locked and loaded for April 25, 2026, featuring plays such as over 7.5 runs in the Athletics vs. Rangers matchup and under 15.5 runs in the Padres vs. Diamondbacks matchup. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are based on current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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