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MLB picks today: Monday's MLB best bets include Red Sox vs. Blue Jays play [4/27/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get MLB picks today and best bets for Monday, April 27, 2026.
Today’s MLB picks for April 27, 2026 are here, with Red Sox vs. Blue Jays and Yankees vs. Rangers among the top plays identified by our model across Monday’s MLB slate.
Dimers’ predictive analytics engine runs 24/7, scanning the latest baseball odds to discover real betting edges. The result? Data-backed plays that help Dimers Pro members make smarter decisions.
List of MLB best bets today [4/27, updated 5:03AM ET]
Below, you’ll find today’s best baseball bets, ranked by edge for Monday, April 27, 2026.
Red Sox vs. Blue Jays over 7 runs (-118)
- Edge: 4.1%
- Probability: 58.2%
- Matchup: Red Sox vs. Blue Jays (7:07PM ET, Monday)
Our model has identified value on over 7 runs in Red Sox vs. Blue Jays at -118 odds. A 58.2% probability produces an edge of 4.1%, making this the strongest play for today's MLB slate.
Yankees vs. Rangers over 8 runs (-112)
- Edge: 3.3%
- Probability: 56.1%
- Matchup: Yankees vs. Rangers (8:05PM ET, Monday)
Yankees vs. Rangers over 8 runs carries a 3.3% edge and a probability of 56.1% at -112 odds, according to our model.
Angels vs. White Sox over 9 runs (-110)
- Edge: 2.9%
- Probability: 55.3%
- Matchup: Angels vs. White Sox (7:40PM ET, Monday)
Angels vs. White Sox over 9 runs at -110 odds shows a 2.9% edge, supported by a 55.3% probability in simulations.
Rays vs. Guardians over 7.5 runs (-110)
- Edge: 2.4%
- Probability: 54.8%
- Matchup: Rays vs. Guardians (6:10PM ET, Monday)
A 2.4% edge and 54.8% probability make Rays vs. Guardians over 7.5 runs at a value play in the Rays vs. Guardians matchup, per our model.
Cubs vs. Padres over 8 runs (-105)
- Edge: 2.3%
- Probability: 53.5%
- Matchup: Cubs vs. Padres (9:40PM ET, Monday)
Cubs vs. Padres over 8 runs at -105 odds presents a 2.3% edge, with simulations resulting in a probability of 53.5%.
MLB best bets summary: Monday, 4/27/2026
As of 5:03AM ET, here are our top MLB bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Probability |
|---|---|---|---|---|
| Red Sox vs. Blue Jays | Over 7 Runs | -118 @ DraftKings | 4.1% | 58.2% |
| Yankees vs. Rangers | Over 8 Runs | -112 @ DraftKings | 3.3% | 56.1% |
| Angels vs. White Sox | Over 9 Runs | -110 @ FanDuel | 2.9% | 55.3% |
| Rays vs. Guardians | Over 7.5 Runs | -110 @ BetMGM | 2.4% | 54.8% |
| Cubs vs. Padres | Over 8 Runs | -105 @ BetMGM | 2.3% | 53.5% |
List of upcoming MLB games to bet on [4/27/2026]
- Rays vs. Guardians (6:10PM ET, Monday)
- Cardinals vs. Pirates (6:40PM ET, Monday)
- Red Sox vs. Blue Jays (7:07PM ET, Monday)
- Angels vs. White Sox (7:40PM ET, Monday)
- Mariners vs. Twins (7:40PM ET, Monday)
- Yankees vs. Rangers (8:05PM ET, Monday)
- Cubs vs. Padres (9:40PM ET, Monday)
- Marlins vs. Dodgers (10:10PM ET, Monday)
Conclusion
Our MLB best bets are locked and loaded for April 27, 2026, featuring plays such as over 7 runs in the Red Sox vs. Blue Jays matchup and over 8 runs in the Yankees vs. Rangers matchup. Powered by advanced simulations, these picks are here to boost your betting game.
Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice, head to our Responsible Gambling hub.
All odds and probabilities in this article are correct and accurate at the time of publication.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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