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Twins vs. Nationals prediction: Close contest projected after new data released for Tuesday's MLB matchup [5/5/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Minnesota Twins vs Washington Nationals predictions for MLB Tuesday.
The Washington Nationals will face the Minnesota Twins, in what is expected to be a close MLB game, at Nationals Park on Tuesday, starting at 6:45 PM ET.
Cade Cavalli (1-1, 3.82 ERA) will be the starting pitcher for the Nationals, while the Twins are going with Taj Bradley (3-1, 2.85 ERA).
Based on updated simulation results, Dimers' proven MLB model gives an equal chance for both both teams to win the Twins-Nationals matchup.
This article offers a closer look at Tuesday's Twins vs. Nationals matchup, including best bets and picks.
Twins vs. Nationals prediction: Who will win?
Using trusted machine learning and data analysis, we have simulated the outcome of Tuesday's MLB matchup between the Twins and Nationals, forming part of our MLB predictions coverage.
Our independent predictive model can't split the two teams, giving both the Twins and Nationals a 50% chance of winning the game.
According to our model, the 9-run over/under has a 53% chance of going over.
Twins vs. Nationals odds [5/5/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Twins | Nationals |
|---|---|---|
| Moneyline | -108 | -104 |
| Total | o9 (-104) | u9 (-110) |
All odds are correct at the time of publication and are subject to change.
Twins vs. Nationals picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Nationals | -104 |
| Total | Over 9 | -104 |
According to our MLB best bets, the top play to make on this game is Over 9 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Twins vs. Nationals game-day updates and essential details
Tuesday's MLB action between the Nationals and Twins at Nationals Park is scheduled to begin at 6:45 PM ET.
- Who: Minnesota Twins vs. Washington Nationals
- Date: Tuesday, May 5, 2026
- Time: 6:45 PM ET/3:45PM PT
- Venue: Nationals Park
Conclusion
We predict a close game between the Twins and Nationals on Tuesday, with each team having a 50% chance of winning.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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