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Heat vs. Bulls prediction: Why Chicago is favored to win Friday's NBA Cup matchup [11/21/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Miami Heat vs Chicago Bulls predictions for NBA Friday.
The Chicago Bulls will face the Miami Heat in NBA Cup action at United Center on Friday, starting at 8:00PM ET.
Based on the latest simulation results and today’s injury news, Dimers' proven NBA model projects the Bulls as the most likely winner of the Heat vs. Bulls game.
This prediction follows the latest NBA Injury Report, which suggests the Bulls lineup will feature players like Josh Giddey, Nikola Vucevic and Matas Buzelis, while the Heat will be led by Norman Powell, Bam Adebayo and Jaime Jaquez.
This article offers a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Heat vs. Bulls prediction: Who will win NBA Cup game?
As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Friday's clash between the Heat and Bulls.
Our leading predictive model currently gives the Bulls a 59% chance of defeating the Heat. Our predicted final score has the Bulls winning 124-122.
According to our model, the Bulls (-2.5) have a 52% chance of covering the spread, while the over/under total of 250.5 points has a 56% chance of staying under.
Heat vs. Bulls odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Heat | Bulls |
|---|---|---|
| Spread | +2.5 (-112) | -2.5 (-105) |
| Moneyline | +115 | -126 |
| Total | o250.5 (-108) | u250.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Heat vs. Bulls picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Bulls -2.5 | -105 |
| Moneyline | Bulls | -126 |
| Total | Under 250.5 | -110 |
According to our best NBA bets for Friday, the top play to make on this game is Under 250.5 total points.
Heat vs. Bulls player props
Betting on Miami vs. Chicago NBA player props? We use the best information available to project how each team's leading players will perform at United Center.
Norman Powell is expected to lead the Heat with 23 points, 3 rebounds and 3 assists, while Josh Giddey is projected to have 20 points, 10 rebounds and 9 assists for the Bulls.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.
Heat prediction
Our model's projected player stats for the Heat are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Norman Powell | 23 | 3 | 3 | 3 | 37 |
| Bam Adebayo | 20 | 9 | 3 | 2 | 41 |
| Jaime Jaquez | 16 | 8 | 6 | 1 | 39 |
| Pelle Larsson | 12 | 4 | 3 | 2 | 26 |
| Davion Mitchell | 12 | 3 | 7 | 2 | 30 |
Bulls prediction
Projected points, rebounds, assists and three-pointers made for the Bulls:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Josh Giddey | 20 | 10 | 9 | 2 | 53 |
| Nikola Vucevic | 17 | 10 | 3 | 2 | 39 |
| Matas Buzelis | 14 | 5 | 2 | 2 | 27 |
| Ayo Dosunmu | 12 | 3 | 4 | 1 | 26 |
| Kevin Huerter | 11 | 3 | 3 | 2 | 23 |
Heat vs. Bulls game-day updates and essential details
Friday's game between the Bulls and Heat at United Center is scheduled to begin at 8:00PM ET.
- Who: Miami Heat vs. Chicago Bulls
- Date: Friday, November 21, 2025
- Time: 8:00PM ET/5:00PM PT
- Venue: United Center
- Tournament details: 2025 Emirates NBA Cup
Conclusion
We predict the Bulls, with a 59% win probability, will likely beat the Heat on Friday, with Josh Giddey projected for a game-high 53 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Heat vs. Bulls insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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