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Grizzlies vs. Spurs prediction: San Antonio favored to win Tuesday's NBA game [12/2/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Memphis Grizzlies vs San Antonio Spurs predictions for NBA Tuesday.
The San Antonio Spurs will square off with the Memphis Grizzlies in NBA action at Frost Bank Center on Tuesday, commencing at 8:00PM ET.
Based on the latest simulation results and today’s injury news, Dimers' proven NBA model predicts the Spurs as the most likely winner of the Grizzlies vs. Spurs game.
This prediction follows the latest NBA Injury Report, which suggests the Spurs lineup will feature players like De'Aaron Fox, Devin Vassell and Harrison Barnes, while the Grizzlies will be led by Jaren Jackson, Cedric Coward and Zach Edey.
This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Grizzlies vs. Spurs prediction: Who will win and cover?
As part of Dimers' NBA predictions coverage—and following a review of recent results—our pregame model has generated moneyline, spread, and over/under probabilities for Tuesday's clash between the Grizzlies and Spurs.
Our famous predictive model currently gives the Spurs a 69% chance of defeating the Grizzlies. Our predicted final score has the Spurs winning 118-113.
According to our model, the Spurs (-5.5) have a 51% chance of covering the spread, while the 232.5-point over/under has a 51% chance of staying under.
Grizzlies vs. Spurs odds
We have researched the best NBA odds in America for this game, which are listed here:
| Bet Type | Grizzlies | Spurs |
|---|---|---|
| Spread | +5.5 (-115) | -5.5 (-102) |
| Moneyline | +172 | -205 |
| Total | o232.5 (-106) | u232.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Grizzlies vs. Spurs picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Spurs -5.5 | -102 |
| Moneyline | Spurs | -205 |
| Total | Under 232.5 | -110 |
According to our best NBA bets for Tuesday, the top play to make on this game is Spurs to win.
Grizzlies vs. Spurs player props
Betting on Memphis vs. San Antonio NBA prop bets? We use the best information available to project how each team's leading players will perform at Frost Bank Center.
Jaren Jackson is expected to lead the Grizzlies with 20 points, 5 rebounds and 2 assists, while De'Aaron Fox is projected to have 24 points, 4 rebounds and 6 assists for the Spurs.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.
Grizzlies prediction
Our model's projected player stats for the Grizzlies are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Jaren Jackson | 20 | 5 | 2 | 2 | 36 |
| Cedric Coward | 14 | 6 | 3 | 2 | 30 |
| Zach Edey | 13 | 12 | 2 | 0 | 37 |
| Jaylen Wells | 12 | 4 | 2 | 2 | 23 |
| Santi Aldama | 12 | 5 | 3 | 2 | 27 |
Spurs prediction
Projected points, rebounds, assists and three-pointers made for the Spurs:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| De'Aaron Fox | 24 | 4 | 6 | 2 | 45 |
| Devin Vassell | 17 | 4 | 3 | 3 | 31 |
| Harrison Barnes | 14 | 4 | 2 | 2 | 26 |
| Keldon Johnson | 14 | 6 | 2 | 1 | 28 |
| Dylan Harper | 13 | 3 | 3 | 1 | 25 |
Grizzlies vs. Spurs game-day updates and essential details
Tuesday's matchup between the Spurs and Grizzlies at Frost Bank Center is scheduled to commence at 8:00PM ET.
- Who: Memphis Grizzlies vs. San Antonio Spurs
- Date: Tuesday, December 2, 2025
- Time: 8:00PM ET/5:00PM PT
- Venue: Frost Bank Center
Conclusion
We predict the Spurs, with a 69% win probability, will likely beat the Grizzlies on Tuesday, with De'Aaron Fox projected for a game-high 45 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate Grizzlies vs. Spurs insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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