Dodgers vs. Padres Prediction: Dodgers Predicted to Win Wednesday's MLB Matchup [6/11/2025]

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Written by Dave Garofolo

Our expert prediction for Wednesday's Los Angeles Dodgers vs San Diego Padres matchup.

Los Angeles Dodgers-San Diego Padres Predictions and Game Preview.
PETCO Park sets the stage for the MLB matchup between the Los Angeles Dodgers and San Diego Padres this Wednesday.

The San Diego Padres and Los Angeles Dodgers will meet in MLB action at PETCO Park on Wednesday, starting at 4:10PM ET.

Randy Vásquez (3-4, 3.70 ERA) will start on the mound for the Padres, while the Dodgers will counter with Ben Casparius (4-1, 2.92 ERA).

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Dodgers as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's LA Dodgers-San Diego game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Dodgers' chance of winning at 55%, with the Padres at 45%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Dodgers vs. Padres predictions page.

Padres vs. Dodgers Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's MLB matchup between the Dodgers and Padres 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Dodgers a 55% chance of defeating the Padres.

According to our model, the Padres (+1.5) have a 57% chance of covering the run line, while the 9.5-run over/under has a 53% chance of staying under.

 

Dodgers vs. Padres Odds [6/11/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Dodgers Padres
Run Line -1.5 (+112) +1.5 (-125)
Moneyline -150 +130
Total o9.5 (-110) u9.5 (-105)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Dodgers vs. Padres Picks and Best Bets

Our model's biggest edge in today's Dodgers vs. Padres matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Dodgers vs. Padres Game-Day Updates and Essential Details

Wednesday's MLB game between the Padres and Dodgers at PETCO Park is scheduled to commence at 4:10PM ET.

Dimers.com's in-depth preview of Wednesday's Dodgers vs. Padres matchup includes our prediction, picks and the latest betting odds.

Before making any LA Dodgers vs. San Diego picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Dodgers, with a 55% win probability, will likely beat the Padres on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Dodgers vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on MLB

Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds provide the most up-to-date probabilities for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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