Holger Rune vs. Mackenzie McDonald Prediction, Odds, Picks for ATP Cinch Championships 2025

Holger Rune will face Mackenzie McDonald in the round of 16 at the ATP London event on Wednesday.

Based on updated simulation results, Dimers' proven tennis model (see Dimers Pro for full access) predicts Holger Rune as the most likely winner of the match.

"We have simulated the outcome of Wednesday's Rune-McDonald match 10,000 times," said Dimers data analyst Greg Butyn.

"With the latest updates and numerous other variables, we estimate Holger Rune's chance of winning at 63%, with Mackenzie McDonald at 37%."

For a closer look at Wednesday's match, including best bets and picks, visit our interactive Rune vs. McDonald predictions page.

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Rune vs. McDonald Prediction: Who Will Win and Advance to the Quarterfinals?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's Rune-McDonald men's singles match 10,000 times as part of our tennis predictions coverage.

Our independent predictive model gives Rune a 63% chance of beating McDonald at the ATP Cinch Championships tournament.

Additionally, Rune has a 59% chance of winning the first set, according to our model.

Pre-Match Probabilities

Last Updated: 10:05PM, Jun 18

Moneyline

1st Set

HolgerRune

Win %

63%

37%

-278

+220

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See Matchup

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MackenzieMcDonald

HolgerRune

-278

Win %

63%

37%

See Matchup

MackenzieMcDonald

+220

Get the best bets with Dimers Pro

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For more insights into the growing popularity of betting on the sport, check out our comprehensive analysis of tennis' rise in the U.S. sports betting market.

Holger Rune vs. Mackenzie McDonald Odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

All odds are correct at the time of publication and are subject to change.

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Rune vs. McDonald Picks and Best Bets

Our model's biggest edge in today's Rune vs. McDonald match is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

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Rune vs. McDonald Updates and Essential Details

The ATP Cinch Championships match between Holger Rune and Mackenzie McDonald is scheduled to begin on Wednesday at 2:10PM ET.

• Who: Holger Rune vs. Mackenzie McDonald
• Date: Wednesday, June 18, 2025
• Approx. Time: 2:10PM ET/11:10AM PT
• Tournament: ATP London, Great Britain Men's Singles 2025
• Round: Round of 16

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's in-depth preview of Wednesday's Rune vs. McDonald match includes our prediction, picks and the latest betting odds.

Before making any Holger Rune vs. Mackenzie McDonald picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key Tennis Betting Guides and Insights

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• Explore where sports odds come from and how they’re applied to tennis matches
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Conclusion

We predict Holger Rune, with a 63% win probability, will likely beat Mackenzie McDonald at the ATP Cinch Championships tournament.

AI and automation have enhanced this article to quickly deliver accurate Rune vs. McDonald insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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