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Read Article Guardians vs. Reds Prediction: Cincinnati Predicted to Win Sunday's MLB Matchup [5/18/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Our expert prediction for Sunday's Cleveland Guardians vs Cincinnati Reds matchup.
The Cincinnati Reds will face the Cleveland Guardians in MLB action at Great American Ball Park on Sunday, starting at 1:40PM ET.
The Reds will send Andrew Abbott (2-0, 2.10 ERA) to the mound, while the Guardians have opted for Luis L. Ortiz (2-4, 4.78 ERA).
Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Reds as the most likely winner of today's game.
"Using the most recent data, our experts ran 10,000 simulations of Sunday's Cleveland-Cincinnati game," said Dimers' Chief Content Officer, Nick Slade.
"After accounting for recent updates and other variables, our prediction shows the Reds with a win probability of 55%, while the Guardians have 45%."
For further insights into Sunday's matchup, including best bets and picks, visit our interactive Guardians vs. Reds predictions page.
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Using innovative machine learning and statistical analysis, we have simulated the outcome of Sunday's MLB game between the Guardians and Reds 10,000 times as part of our MLB predictions coverage.
Our independent predictive model currently gives the Reds a 55% chance of beating the Guardians.
According to our model, the Guardians (+1.5) have a 64% chance of covering the run line, while the 9-run over/under has a 56% chance of staying under.
Pre-Game Probabilities
Last Updated: 5:27PM, May 18
Moneyline
Over / Under
Run Line
Luis Ortiz 2-4, 4.78 ERA
Andrew Abbott 2-0, 2.10 ERA
Get the best bets with Dimers Pro
Guardians vs. Reds Odds [5/18/2025]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Guardians | Reds |
|---|---|---|
| Run Line | +1.5 (-176) | -1.5 (+165) |
| Moneyline | +116 | -130 |
| Total | o9 (+100) | u9 (-115) |
All odds are correct at the time of publication and are subject to change.
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Guardians vs. Reds Picks and Best Bets
Our model's biggest edge in today's Guardians vs. Reds matchup is on the run line.
Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.
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Calling Our Shot produces daily MLB betting content, including the free picks featured below.
Guardians vs. Reds Game-Day Updates and Essential Details
Sunday's MLB action between the Reds and Guardians at Great American Ball Park is scheduled to start at 1:40PM ET.
- Who: Cleveland Guardians vs. Cincinnati Reds
- Date: Sunday, May 18, 2025
- Time: 1:40PM ET/10:40AM PT
- Venue: Great American Ball Park
Dimers.com's comprehensive preview of Sunday's Guardians vs. Reds matchup includes our prediction, picks and the latest betting odds.
Before making any Cleveland vs. Cincinnati picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
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Conclusion
We predict the Reds, with a 55% win probability, will likely beat the Guardians on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Guardians vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on MLB
Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest predictions for the World Series, American League, National League and each division.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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