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Cavaliers vs. Knicks prediction: New York to win, Jalen Brunson projected for big game in Thursday's NBA matchup [12/25/2025]

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Written by Ryan Leaver

Get Cleveland Cavaliers vs New York Knicks predictions for NBA Thursday.

Cleveland Cavaliers-New York Knicks Predictions and Game Preview.
Cleveland Cavaliers vs. New York Knicks NBA prediction for Thursday, December 25, 2025.

The New York Knicks will take on the Cleveland Cavaliers in NBA action at Madison Square Garden on Christmas Day, commencing at 12:00 PM ET.

Based on updated simulation results and today’s injury updates, Dimers' proven NBA model projects the Knicks as the most likely winner of the Cavaliers vs. Knicks game.

This prediction follows the latest NBA Injury Report, which suggests the Knicks lineup will feature stars like Jalen Brunson, Karl-Anthony Towns and OG Anunoby, while the Cavaliers will look to Donovan Mitchell, Darius Garland and De'Andre Hunter.

This article offers a closer look at Thursday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Cavs vs. Knicks prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Thursday's NBA matchup between the Cavaliers and Knicks 10,000 times as part of our NBA predictions coverage.

Our leading predictive model gives the Knicks a 67% chance of beating the Cavaliers. Our predicted final score has the Knicks winning 121-116.

According to our model, the Cavaliers (+5.5) have a 52% chance of covering the spread, while the 240.5-point over/under has a 53% chance of staying under.

 

Cavaliers vs. Knicks odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type Cavaliers Knicks
Spread +5.5 (-105) -5.5 (-108)
Moneyline +190 -210
Total o240.5 (-105) u240.5 (-108)

All odds are correct at the time of publication and are subject to change.

Cavaliers vs. Knicks picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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