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St Kilda Saints vs. Brisbane Lions prediction: Lions favored to win Friday's AFL Round 3 matchup [3/27/2026]

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Written by Damien Souness

Get St Kilda Saints vs Brisbane Lions predictions for AFL Friday.

St Kilda Saints-Brisbane Lions Predictions and Game Preview.
St Kilda Saints vs. Brisbane Lions AFL prediction for Friday, March 27, 2026.

The St Kilda Saints and Brisbane Lions will meet in the Australian Football League (AFL) at Marvel Stadium on Friday, starting at 9:35 PM ET.

Based on the latest simulation results, Dimers' proven AFL model predicts the Lions as the most likely winner of the Lions vs. Saints game.

This article offers further insights into Friday's matchup, including best bets and picks.

Saints vs. Lions prediction: Who will win Round 3 game?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Friday's AFL matchup between the Lions and Saints, forming part of our AFL predictions coverage.

Our famous predictive model gives the Lions a 62% chance of defeating the Saints.

According to our model, the Lions (-9.5) have a 51% chance of covering the spread, while the 187.5-point over/under has a 52% chance of staying under.

 

Brisbane vs. St Kilda odds

We have researched the best AFL odds in America for this game, which are listed here:

Bet Type Lions Saints
H2H (Moneyline) -161 +125
Line (Spread) -9.5 (-115) +9.5 (-115)
Total o187.5 (-115) u187.5 (-115)

All odds are correct at the time of publication and are subject to change.

Lions vs. Saints picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Damien Souness
Chief Innovation Officer

Damien Souness leverages over 15 years of experience to create engaging content focused on sports, online gaming and wagering. As Chief Innovation Officer at Cipher Sports Technology Group, the parent company of Dimers, he offers strategic insights and innovative solutions to enhance the player experience.

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