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North Melbourne Kangaroos vs. Brisbane Lions prediction: Lions favored to win Friday's AFL Round 5 matchup [4/10/2026]

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Written by Damien Souness

Get North Melbourne Kangaroos vs Brisbane Lions predictions for AFL Friday.

North Melbourne Kangaroos-Brisbane Lions Predictions and Game Preview.
North Melbourne Kangaroos vs. Brisbane Lions AFL prediction for Friday, April 10, 2026.

The North Melbourne Kangaroos and Brisbane Lions will meet in the Australian Football League (AFL) at Barossa Park on Friday, starting at 10:35 PM ET.

Based on the latest simulation results, Dimers' advanced AFL model predicts the Lions as the most likely winner of the Lions vs. Kangaroos game.

This article offers a closer look at Friday's matchup, including best bets and picks.

Kangaroos vs. Lions prediction: Who will win Round 5 game?

Using powerful machine learning and data, we have simulated the outcome of Friday's AFL game between the Lions and Kangaroos, forming part of our AFL predictions coverage.

Our independent predictive model currently gives the Lions an 84% chance of beating the Kangaroos.

According to our model, the Kangaroos (+39.5) have a 57% chance of covering the spread, while the over/under total of 192.5 points has a 51% chance of staying under.

 

Brisbane vs. North Melbourne odds

We have sourced the best AFL odds in America for this game, which are listed here:

Bet Type Lions Kangaroos
H2H (Moneyline) -909 +500
Line (Spread) -39.5 (-115) +39.5 (-115)
Total o192.5 (-115) u192.5 (-115)

All odds are correct at the time of publication and are subject to change.

Lions vs. Kangaroos picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Damien Souness
Chief Innovation Officer

Damien Souness leverages over 15 years of experience to create engaging content focused on sports, online gaming and wagering. As Chief Innovation Officer at Cipher Sports Technology Group, the parent company of Dimers, he offers strategic insights and innovative solutions to enhance the player experience.

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