North Melbourne Kangaroos vs. Brisbane Lions prediction: Lions favored to win Friday's AFL Round 5 matchup [4/10/2026]

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Written by Damien Souness

Get North Melbourne Kangaroos vs Brisbane Lions predictions for AFL Friday.

North Melbourne Kangaroos-Brisbane Lions Predictions and Game Preview.
North Melbourne Kangaroos vs. Brisbane Lions AFL prediction for Friday, April 10, 2026.

The North Melbourne Kangaroos and Brisbane Lions will meet in the Australian Football League (AFL) at Barossa Park on Friday, starting at 10:35 PM ET.

Based on the latest simulation results, Dimers' advanced AFL model projects the Lions as the most likely winner of the Lions vs. Kangaroos game.

This article offers a closer look at Friday's matchup, including best bets and picks.

Kangaroos vs. Lions prediction: Who will win Round 5 game?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Friday's AFL game between the Lions and Kangaroos, forming part of our AFL predictions coverage.

Our famous predictive model gives the Lions an 83% chance of defeating the Kangaroos.

According to our model, the Kangaroos (+40.5) have a 60% chance of covering the spread, while the over/under total of 182.5 points has a 51% chance of staying under.

 

Brisbane vs. North Melbourne odds

We have researched the best AFL odds in America for this game, which are listed here:

Bet Type Lions Kangaroos
H2H (Moneyline) -909 +550
Line (Spread) -40.5 (-115) +40.5 (-115)
Total o182.5 (-115) u182.5 (-115)

All odds are correct at the time of publication and are subject to change.

Lions vs. Kangaroos picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Kangaroos +40.5 -115
Moneyline Kangaroos +550
Total Under 182.5 -115

According to our AFL best bets, the top play to make on this game is Kangaroos +40.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Kangaroos vs. Lions game-day updates and essential details

Friday's Australian rules football game between the Kangaroos and Lions at Barossa Park is scheduled to start at 10:35 PM ET.

  • Who: Brisbane Lions vs. North Melbourne Kangaroos
  • Date: Friday, April 10, 2026
  • Time: 10:35 PM ET/7:35PM PT
  • Venue: Barossa Park

The AFL is available to bet on in the US through all major sportsbooks, with fans highlighting the high-octane 360-degree nature of the sport as a top reason to follow it.

Conclusion

We predict the Lions, with an 83% win probability, will likely beat the Kangaroos in Friday's AFL matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Damien Souness
Chief Experience Officer

Damien Souness is Chief Experience Officer at Cipher Sports Technology Group, helping lead sports media brands such as Dimers. He specializes in creating trustworthy and data-driven content for sports fans, with experience working for globally recognized sports and media organizations.

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