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Red Sox vs. Blue Jays prediction: Why Toronto is favored to win Wednesday's MLB matchup [4/29/2026]
Get Boston Red Sox vs Toronto Blue Jays predictions for MLB Wednesday.

The Toronto Blue Jays and Boston redsox will lock horns in MLB action at Rogers Centre on Wednesday, starting at 3:07 PM ET.
Eric Lauer (1-3, 6.75 ERA) will start on the mound for the Blue Jays, while the Red Sox will counter with Brayan Bello (1-3, 9.00 ERA).
Based on the latest simulation results, Dimers' advanced MLB model predicts the Blue Jays as the most likely winner of the Red Sox vs. Blue Jays game.
This article offers a closer look at Wednesday's matchup, including best bets and picks.
Red Sox vs. Blue Jays prediction: Who will win and cover?
Our famous predictive model gives the Blue Jays a 56% chance of beating the Red Sox.
According to our model, the Red Sox (+1.5) have a 61% chance of covering the run line, while the 8.5-run over/under has a 53% chance of going over.
Red Sox vs. Blue Jays odds [4/29/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Red Sox | Blue Jays |
|---|---|---|
| Run Line | +1.5 (-190) | -1.5 (+159) |
| Moneyline | +113 | -130 |
| Total | o8.5 (+100) | u8.5 (-120) |
All odds are correct at the time of publication and are subject to change.
Red Sox vs. Blue Jays picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Blue Jays -1.5 | +159 |
| Moneyline | Blue Jays | -130 |
| Total | Over 8.5 | +100 |
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Red Sox vs. Blue Jays game-day updates and essential details
Wednesday's MLB game between the Blue Jays and Red Sox at Rogers Centre is scheduled to start at 3:07 PM ET.
- Who: Boston Red Sox vs. Toronto Blue Jays
- Date: Wednesday, April 29, 2026
- Time: 3:07 PM ET/12:07PM PT
- Venue: Rogers Centre
Conclusion
We predict the Blue Jays, with a 56% win probability, will likely beat the Red Sox in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
