Red Sox vs. Giants Prediction: San Francisco Predicted to Win Sunday's MLB Matchup [6/22/2025]

MLB action continues on Sunday at 4:05PM ET as the Boston Red Sox take on the San Francisco Giants at Oracle Park.

Robbie Ray (8-2, 2.68 ERA) will start for the Giants, while the Red Sox have opted for Lucas Giolito (3-1, 4.73 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Giants as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Red Sox-Giants game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Giants with a win probability of 61%, while the Red Sox have 39%."

For a closer look at Sunday's matchup, including best bets and picks, visit our interactive Red Sox vs. Giants predictions page.

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Giants vs. Red Sox Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Sunday's MLB matchup between the Red Sox and Giants 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Giants a 61% chance of beating the Red Sox.

According to our model, the Red Sox (+1.5) have a 59% chance of covering the run line, while the 7.5-run over/under has a 55% chance of staying under.

Pre-Game Probabilities

Last Updated: 8:32PM, Jun 22

Moneyline

Over / Under

Run Line

Red Sox

Win %

49%

51%

+140

-160

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Giants

Red Sox BOS

+140

Win %

49%

51%

See Matchup

Giants SF

-160

Lucas Giolito 3-1, 4.73 ERA

Robbie Ray 8-2, 2.68 ERA

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Red Sox vs. Giants Odds [6/22/2025]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Red Sox vs. Giants Picks and Best Bets

Our model's strongest edge in today's Red Sox vs. Giants matchup is on the run line.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Best Bets Today

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Red Sox vs. Giants Game-Day Updates and Essential Details

Sunday's MLB matchup between the Giants and Red Sox at Oracle Park is scheduled to begin at 4:05PM ET.

• Who: Boston Red Sox vs. San Francisco Giants
• Date: Sunday, June 22, 2025
• Time: 4:05PM ET/1:05PM PT
• Venue: Oracle Park

Dimers.com's full preview of Sunday's Red Sox vs. Giants matchup includes our prediction, picks and the latest betting odds.

Before making any Red Sox vs. Giants picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Giants, with a 61% win probability, will likely beat the Red Sox on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Red Sox vs. Giants insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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