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Celtics vs. Pacers prediction: Why Boston is favored to win Friday's NBA matchup [12/26/2025]

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Written by Ryan Leaver

Get Boston Celtics vs Indiana Pacers predictions for NBA Friday.

Boston Celtics-Indiana Pacers Predictions and Game Preview.
Boston Celtics vs. Indiana Pacers NBA prediction for Friday, December 26, 2025.

NBA action continues on Friday at 7:00 PM ET as the favored Boston Celtics square off with the Indiana Pacers at Gainbridge Fieldhouse.

Based on the latest simulation results and today’s injury updates, Dimers' proven NBA model projects the Celtics as the most likely winner of the Celtics vs. Pacers game.

This prediction follows the latest NBA Injury Report, which suggests the Pacers lineup will feature stars like Pascal Siakam, Bennedict Mathurin and Andrew Nembhard, while the Celtics will rely on Jaylen Brown, Derrick White and Payton Pritchard.

This article offers a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Celtics vs. Pacers prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Friday's NBA game between the Celtics and Pacers 10,000 times as part of our NBA predictions coverage.

Our famous predictive model currently gives the Celtics a 74% chance of defeating the Pacers. Our predicted final score has the Celtics winning 114-107.

According to our model, the Pacers (+8.5) have a 54% chance of covering the spread, while the over/under total of 222.5 points has a 51% chance of going over.

 

Celtics vs. Pacers odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Celtics Pacers
Spread -8.5 (-112) +8.5 (-105)
Moneyline -325 +275
Total o222.5 (-108) u222.5 (-110)

All odds are correct at the time of publication and are subject to change.

Celtics vs. Pacers picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Pacers +8.5 -105
Moneyline Pacers +275
Total Over 222.5 -108

According to our best NBA bets for Friday, the top play to make on this game is Pacers +8.5 at the spread.

 

Celtics vs. Pacers player props

NBA player props are an enjoyable way to wager on Friday's Celtics vs. Pacers game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Gainbridge Fieldhouse.

Jaylen Brown is expected to lead the Celtics with 28 points, 6 rebounds and 4 assists, while Pascal Siakam is projected to have 23 points, 6 rebounds and 4 assists for the Pacers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Celtics prediction

Our model's projected player stats for the Celtics are:

Player PTS REB AST 3PM DFS
Jaylen Brown 28 6 4 2 48
Derrick White 17 5 4 3 37
P. Pritchard 15 5 4 3 31
Anfernee Simons 12 2 2 2 20
Neemias Queta 10 8 2 0 26

Pacers prediction

Projected points, rebounds, assists and three-pointers made for the Pacers:

Player PTS REB AST 3PM DFS
Pascal Siakam 23 6 4 2 40
B. Mathurin 17 6 2 2 32
Andrew Nembhard 15 3 6 2 31
Jay Huff 10 5 1 2 25
T.J. McConnell 9 3 4 0 21

Celtics vs. Pacers game-day updates and essential details

Friday's matchup between the Pacers and Celtics at Gainbridge Fieldhouse is scheduled to commence at 7:00 PM ET.

Conclusion

We predict the Celtics, with a 74% win probability, will likely beat the Pacers on Friday, with Jaylen Brown projected for a game-high 48 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Celtics vs. Pacers insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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