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Alex de Minaur vs. Lorenzo Musetti Prediction, Odds, Picks for ATP Madrid Open 2025
Our expert prediction for Wednesday's Alex de Minaur vs Lorenzo Musetti matchup.

Alex de Minaur will square off with Lorenzo Musetti in the round of 16 at the ATP Madrid event on Wednesday.
Based on updated simulation results, Dimers' proven tennis model (see Dimers Pro for full access) predicts Alex de Minaur as the most likely winner of the match.
"We have simulated the outcome of Wednesday's de Minaur-Musetti match 10,000 times," said Dimers data analyst Greg Butyn.
"With the latest updates and numerous other variables, we estimate Alex de Minaur's chance of winning at 57%, with Lorenzo Musetti at 43%."
For a closer look at Wednesday's match, including best bets and picks, visit our interactive de Minaur vs. Musetti predictions page.
de Minaur vs. Musetti Prediction: Who Will Win and Advance to the Quarterfinals?
Using trusted machine learning and data analysis, we have simulated the result of Wednesday's de Minaur-Musetti men's singles match 10,000 times as part of our tennis predictions coverage.
Our independent predictive model currently gives de Minaur a 57% chance of defeating Musetti at the ATP Madrid Open tournament.
Additionally, de Minaur has a 55% chance of winning the first set, according to our model.
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Alex de Minaur vs. Lorenzo Musetti Odds
We have researched the most up-to-date betting odds in America for this match, which are listed here:
| Bet Type | de Minaur | Musetti |
|---|---|---|
| Moneyline | -152 | +120 |
| First Set | -139 | +110 |
All odds are correct at the time of publication and are subject to change.
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de Minaur vs. Musetti Picks and Best Bets
Our model's strongest edge in today's de Minaur vs. Musetti match is on the moneyline.
Our expert predictions, matched against the latest odds, reveal the best tennis picks and tennis best bets for every match throughout the year.
Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.
de Minaur vs. Musetti Updates and Essential Details
The ATP Madrid Open match between Alex de Minaur and Lorenzo Musetti is scheduled to commence on Wednesday at 4:55PM ET.
- Who: Alex de Minaur vs. Lorenzo Musetti
- Date: Wednesday, April 30, 2025
- Approx. Time: 4:55PM ET/1:55PM PT
- Tournament: ATP Madrid, Spain Men's Singles 2025
- Round: Round of 16
All dates and times mentioned in this article are United States Eastern Time unless otherwise noted.
Dimers.com's in-depth preview of Wednesday's de Minaur vs. Musetti match includes our prediction, picks and the latest betting odds.
Before making any Alex de Minaur vs. Lorenzo Musetti picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.
Key Tennis Betting Guides and Insights
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- Explore where sports odds come from and how they’re applied to tennis matches
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- Improve your chances with proven sports betting strategies that apply to tennis and more
Conclusion
We predict Alex de Minaur, with a 57% win probability, will likely beat Lorenzo Musetti at the ATP Madrid Open tournament.
AI and automation have enhanced this article to quickly deliver accurate de Minaur vs. Musetti insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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