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Xavier vs. Seton Hall prediction: Seton Hall favored to win men's college basketball matchup [1/28/2026]

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Written by Mac Douglass

Get Xavier vs Seton Hall predictions for college basketball Wednesday.

Xavier-Seton Hall Predictions and Game Preview.
Xavier vs. Seton Hall men's college basketball prediction for Wednesday, January 28, 2026.

Seton Hall will take on Xavier in men's college basketball action at Prudential Center on Wednesday, commencing at 7:30 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts Seton Hall as the most likely winner of the Xavier vs. Seton Hall game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Xavier vs. Seton Hall prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball game between Xavier and Seton Hall 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Seton Hall a 73% chance of beating Xavier. Our predicted final score has Seton Hall winning 75-69.

According to our model, Xavier (+5.5) has a 51% chance of covering the spread, while the 145.5-point over/under has a 52% chance of going over.

 

Xavier vs. Seton Hall odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Xavier Seton Hall
Spread +5.5 (-106) -5.5 (-112)
Moneyline +220 -258
Total o145.5 (-110) u145.5 (-108)

All odds are correct at the time of publication and are subject to change.

Xavier vs. Seton Hall picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Xavier +5.5 -106
Moneyline Seton Hall -258
Total Over 145.5 -110

According to our best men's college basketball bets, the top play to make on this game is Seton Hall to win.

 

Xavier vs. Seton Hall game-day updates and essential details

Wednesday's men's college basketball game between Seton Hall and Xavier at Prudential Center is scheduled to start at 7:30 PM ET.

  • Who: Xavier vs. Seton Hall
  • Date: Wednesday, January 28, 2026
  • Time: 7:30 PM ET/4:30PM PT
  • Venue: Prudential Center

Conclusion

We predict Seton Hall, with a 73% win probability, will likely beat Xavier on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Xavier vs. Seton Hall insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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