Xavier vs. Marquette prediction: Why Marquette is favored to win men's college basketball matchup [1/7/2026]

Marquette will take on Xavier in men's college basketball action at Fiserv Forum on Wednesday, commencing at 7:00 PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts Marquette as the most likely winner of the Xavier vs. Marquette game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Xavier vs. Marquette prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball game between Xavier and Marquette 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Marquette a 69% chance of beating Xavier. Our predicted final score has Marquette winning 79-73.

According to our model, Xavier (+5.5) has a 52% chance of covering the spread, while the over/under total of 157.5 points has a 55% chance of staying under.

Xavier vs. Marquette odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Xavier vs. Marquette picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: