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Xavier vs. DePaul prediction: DePaul favored to win men's college basketball matchup [1/3/2026]

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Written by Dave Garofolo

Get Xavier vs DePaul predictions for college basketball Saturday.

Xavier-DePaul Predictions and Game Preview.
Xavier vs. DePaul men's college basketball prediction for Saturday, January 3, 2026.

DePaul will face Xavier in men's college basketball action at Wintrust Arena on Saturday, beginning at 2:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model projects DePaul as the most likely winner of the Xavier vs. DePaul game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Xavier vs. DePaul prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between Xavier and DePaul 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives DePaul a 59% chance of defeating Xavier. Our predicted final score has DePaul winning 75-72.

According to our model, Xavier (+2.5) has a 51% chance of covering the spread, while the 149.5-point over/under has a 53% chance of staying under.

 

Xavier vs. DePaul odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Xavier DePaul
Spread +2.5 (-105) -2.5 (-110)
Moneyline +126 -148
Total o149.5 (-110) u149.5 (-108)

All odds are correct at the time of publication and are subject to change.

Xavier vs. DePaul picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Xavier +2.5 -105
Moneyline DePaul -148
Total Under 149.5 -108

According to our men's college basketball best bets, the top play to make on this game is Under 149.5 total points.

 

Xavier vs. DePaul game-day updates and essential details

Saturday's men's college basketball matchup between DePaul and Xavier at Wintrust Arena is scheduled to commence at 2:00 PM ET.

  • Who: Xavier vs. DePaul
  • Date: Saturday, January 3, 2026
  • Time: 2:00 PM ET/11:00AM PT
  • Venue: Wintrust Arena

Conclusion

We predict DePaul, with a 59% win probability, will likely beat Xavier on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Xavier vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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