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Women's college basketball picks today: Thursday's best bets include LSU vs. Duke play [12/4/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get the best bets for Thursday, December 4, 2025.
Today’s women's college basketball picks for December 04, 2025 are here, with LSU vs. Duke among the top plays identified by our model across Thursday’s women's basketball action.
Dimers’ predictive analytics engine runs 24/7, scanning the latest women's basketball odds to discover top betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.
List of NCAAW picks tonight [12/4, updated 8:32PM ET]
Below, you’ll find today’s best women's college basketball bets, ranked by edge for Thursday, December 4, 2025.
Duke ML (+1200)
- Edge: 17.3%
- Probability: 25%
- Matchup: LSU vs. Duke (9:00PM ET, Thursday)
Our model has identified value on Duke to defeat LSU at +1200 odds. A 25% probability produces an edge of 17.3%, making this the strongest play for today's women's college basketball slate.
Duke +15.5 (-105)
- Edge: 15.6%
- Probability: 66.8%
- Matchup: LSU vs. Duke (9:00PM ET, Thursday)
Duke +15.5 carries a 15.6% edge and a probability of 66.8% at -105 odds, according to our model.
LSU vs. Duke over 148.5 points (-110)
- Edge: 10.9%
- Probability: 63.3%
- Matchup: LSU vs. Duke (9:00PM ET, Thursday)
LSU vs. Duke over 148.5 points at -110 odds shows a 10.9% edge, supported by a 63.3% probability in simulations.
Notre Dame +3.5 (-110)
- Edge: 7.3%
- Probability: 59.7%
- Matchup: Notre Dame vs. Ole Miss (9:00PM ET, Thursday)
A 7.3% edge and 59.7% probability make Notre Dame +3.5 vs. Ole Miss at a value play in the Notre Dame vs. Ole Miss matchup, per our model.
Notre Dame ML (+132)
- Edge: 6.7%
- Probability: 49.8%
- Matchup: Notre Dame vs. Ole Miss (9:00PM ET, Thursday)
Notre Dame ML at +132 odds presents a 6.7% edge, with simulations resulting in a probability of 49.8%.
NCAAW best bets summary: Thursday, 12/4/2025
As of 8:32PM ET, here are our top women's college basketball bets by edge recommended by our model:
| Matchup | Bet | Odds | Edge | Probability |
|---|---|---|---|---|
| LSU vs. Duke | Duke ML | +1200 @ FanDuel | 17.3% | 25% |
| LSU vs. Duke | Duke +15.5 | -105 @ FanDuel | 15.6% | 66.8% |
| LSU vs. Duke | Over 148.5 Points | -110 @ DraftKings | 10.9% | 63.3% |
| Notre Dame vs. Ole Miss | Notre Dame +3.5 | -110 @ DraftKings | 7.3% | 59.7% |
| Notre Dame vs. Ole Miss | Notre Dame ML | +132 @ FanDuel | 6.7% | 49.8% |
List of upcoming women's college basketball games to bet on now
- Notre Dame vs. Ole Miss (9:00PM ET, Thursday)
- LSU vs. Duke (9:00PM ET, Thursday)
- Marquette vs. DePaul (9:00PM ET, Thursday)
- California vs. Missouri (9:00PM ET, Thursday)
- Grand Canyon vs. Gonzaga (9:00PM ET, Thursday)
- Hawaii vs. UC Davis (9:00PM ET, Thursday)
Conclusion
Our women's college basketball best bets are locked and loaded for December 4, 2025, featuring plays such as Duke ML and Duke +15.5. Powered by advanced simulations, these picks are here to boost your betting game.
This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
All odds and probabilities in this article are correct and accurate at the time of publication.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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