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Wisconsin vs. Penn State prediction: Why Wisconsin is favored to win men's college basketball matchup [1/22/2026]

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Written by Dave Garofolo

Get Wisconsin vs Penn State predictions for college basketball Thursday.

Wisconsin-Penn State Predictions and Game Preview.
Wisconsin vs. Penn State men's college basketball prediction for Thursday, January 22, 2026.

Penn State will square off with the favored Wisconsin in men's college basketball action at Bryce Jordan Center on Thursday, beginning at 7:00 PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts Wisconsin as the most likely winner of the Wisconsin vs. Penn State game.

This article offers a closer look at Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

Wisconsin vs. Penn State prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Thursday's NCAA basketball game between Wisconsin and Penn State 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Wisconsin a 67% chance of beating Penn State. Our predicted final score has Wisconsin winning 80-76.

According to our model, Penn State (+5.5) has a 55% chance of covering the spread, while the over/under total of 157.5 points has an equal 50-50 chance of hitting.

 

Wisconsin vs. Penn State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Wisconsin Penn State
Spread -5.5 (-112) +5.5 (-105)
Moneyline -250 +220
Total o157.5 (-110) u157.5 (-105)

All odds are correct at the time of publication and are subject to change.

Wisconsin vs. Penn State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Penn State +5.5 -105
Moneyline Penn State +220
Total Under 157.5 -105

According to our men's college basketball best bets, the top play to make on this game is Penn State +5.5 at the spread.

 

Wisconsin vs. Penn State game-day updates and essential details

Thursday's men's college basketball game between Penn State and Wisconsin at Bryce Jordan Center is scheduled to start at 7:00 PM ET.

  • Who: Wisconsin vs. Penn State
  • Date: Thursday, January 22, 2026
  • Time: 7:00 PM ET/4:00PM PT
  • Venue: Bryce Jordan Center

Conclusion

We predict Wisconsin, with a 67% win probability, will likely beat Penn State on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Wisconsin vs. Penn State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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