Winthrop vs. USC Upstate prediction: Winthrop favored to win men's college basketball matchup [1/10/2026]

Men's college basketball action continues on Saturday at 2:00 PM ET as the favored Winthrop takes on USC Upstate in men's college basketball action at G.B. Hodge Center.

Based on the latest simulations, Dimers' advanced college basketball model predicts Winthrop as the most likely winner of the Winthrop vs. USC Upstate game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Winthrop vs. USC Upstate prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Saturday's NCAA basketball game between Winthrop and USC Upstate 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Winthrop a 64% chance of beating USC Upstate. Our predicted final score has Winthrop winning 79-76.

According to our model, USC Upstate (+5.5) has a 58% chance of covering the spread, while the 156.5-point over/under has a 53% chance of staying under.

Winthrop vs. USC Upstate odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Winthrop vs. USC Upstate picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: