Western Kentucky vs. Vanderbilt prediction: Vanderbilt favored to win men's college basketball matchup [11/26/2025]

Vanderbilt will take on Western Kentucky in men's college basketball action at Imperial Arena on Wednesday, starting at 12:00PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts Vanderbilt as the most likely winner of the Western Kentucky vs. Vanderbilt game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Western Kentucky vs. Vanderbilt prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Wednesday's NCAA basketball matchup between Western Kentucky and Vanderbilt 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Vanderbilt a 90% chance of beating Western Kentucky. Our predicted final score has Vanderbilt winning 89-73.

According to our model, Western Kentucky (+17.5) has a 52% chance of covering the spread, while the 167.5-point over/under has a 53% chance of staying under.

Western Kentucky vs. Vanderbilt odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Western Kentucky vs. Vanderbilt picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Western Kentucky to win.

Western Kentucky vs. Vanderbilt game-day updates and essential details

Wednesday's men's college basketball game between Vanderbilt and Western Kentucky at Imperial Arena is scheduled to commence at 12:00PM ET.

• Who: Western Kentucky vs. Vanderbilt
• Date: Wednesday, November 26, 2025
• Time: 12:00PM ET/9:00AM PT
• Venue: Imperial Arena

Conclusion

We predict Vanderbilt, with a 90% win probability, will likely beat Western Kentucky on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Western Kentucky vs. Vanderbilt insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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