Western Illinois vs. Southern Indiana prediction: Southern Indiana favored to win men's college basketball matchup [1/23/2026]

Men's college basketball action continues on Friday at 8:30 PM ET as Western Illinois squares off with Southern Indiana in men's college basketball action at Liberty Arena.

Based on the latest simulation results, Dimers' advanced college basketball model projects Southern Indiana as the most likely winner of the Western Illinois vs. Southern Indiana game.

This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Western Illinois vs. Southern Indiana prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the result of Friday's NCAA basketball matchup between Western Illinois and Southern Indiana 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Southern Indiana a 75% chance of defeating Western Illinois. Our predicted final score has Southern Indiana winning 73-66.

According to our model, Southern Indiana (-6.5) has a 53% chance of covering the spread, while the 136.5-point over/under has a 54% chance of going over.

Western Illinois vs. Southern Indiana odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Western Illinois vs. Southern Indiana picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best men's college basketball bets, the top play to make on this game is Southern Indiana to win.

Western Illinois vs. Southern Indiana game-day updates and essential details

Friday's men's college basketball action between Southern Indiana and Western Illinois at Liberty Arena is scheduled to begin at 8:30 PM ET.

• Who: Western Illinois vs. Southern Indiana
• Date: Friday, January 23, 2026
• Time: 8:30 PM ET/5:30PM PT
• Venue: Liberty Arena

Conclusion

We predict Southern Indiana, with a 75% win probability, will likely beat Western Illinois on Friday.

AI and automation have enhanced this article to quickly deliver accurate Western Illinois vs. Southern Indiana insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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