Western Carolina vs. Duke prediction: Duke favored to win men's college basketball matchup [11/8/2025]

Men's college basketball action continues on Saturday at 1:30PM ET as Western Carolina faces off with the favored Duke in men's college basketball action at Cameron Indoor Stadium.

Based on the latest simulations, Dimers' proven college basketball model predicts Duke as the most likely winner of the Western Carolina vs. Duke game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Western Carolina vs. Duke prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the result of Saturday's NCAA basketball game between Western Carolina and Duke 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Duke a 99% chance of beating Western Carolina. Our predicted final score has Duke winning 90-60.

According to our model, Western Carolina (+36.5) has a 57% chance of covering the spread, while the 152.5-point over/under has a 53% chance of staying under.

Western Carolina vs. Duke odds

We have researched the best Men's College Basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Western Carolina vs. Duke picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best men's college basketball bets, the top play to make on this game is Western Carolina +36.5 at the spread.

Western Carolina vs. Duke game-day updates and essential details

Saturday's men's college basketball game between Duke and Western Carolina at Cameron Indoor Stadium is scheduled to begin at 1:30PM ET.

• Who: Western Carolina vs. Duke
• Date: Saturday, November 8, 2025
• Time: 1:30PM ET/10:30AM PT
• Venue: Cameron Indoor Stadium

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Conclusion

We predict Duke, with a 99% win probability, will likely beat Western Carolina on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Western Carolina vs. Duke insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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