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Wizards vs. Bucks prediction: Milwaukee to win, Giannis Antetokounmpo projected for big game in Wednesday's NBA matchup [10/22/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Washington Wizards vs Milwaukee Bucks predictions for NBA Wednesday.
The Milwaukee Bucks will square off with the Washington Wizards in NBA action at Fiserv Forum on Wednesday, beginning at 8:00PM ET.
Based on the latest simulations and today’s injury updates, Dimers' advanced NBA model predicts the Bucks as the most likely winner of today's game.
"Our team has simulated the outcome of Wednesday's Wizards-Bucks game 10,000 times," said Damien Souness from Dimers.
"With the latest updates and numerous other variables, we estimate the Bucks' chance of winning at 77%, with the Wizards at 23%."
This prediction follows the latest NBA Injury Report, which suggests the Bucks lineup will feature players like Giannis Antetokounmpo, Myles Turner and Kevin Porter, while the Wizards will rely on CJ McCollum, Alex Sarr and Khris Middleton.
For further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Wizards vs. Bucks predictions page.
Wizards vs. Bucks prediction: Who will win, cover the spread?
Using trusted machine learning and statistical analysis, we have simulated the result of Wednesday's NBA game between the Wizards and Bucks 10,000 times as part of our NBA predictions coverage.
Our famous predictive model currently gives the Bucks a 77% chance of defeating the Wizards. Our predicted final score has the Bucks winning 118-110.
According to our model, the Wizards (+10) have a 55% chance of covering the spread, while the 229.5-point over/under has an equal 50-50 chance of hitting.
Wizards vs. Bucks odds
We have sourced the best NBA odds in America for this game, which are listed here:
| Bet Type | Wizards | Bucks |
|---|---|---|
| Spread | +10 (-110) | -10 (-110) |
| Moneyline | +350 | -440 |
| Total | o229.5 (-106) | u229.5 (-114) |
All odds are correct at the time of publication and are subject to change.
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Wizards vs. Bucks picks and best bets
Our model's strongest edge in today's Wizards vs. Bucks matchup is on the total.
Our expert predictions, matched against the best odds, reveal the best NBA picks and NBA best bets for every game throughout the season.
Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.
Wizards vs. Bucks player props
Looking for Washington vs. Milwaukee NBA player props? We use the best information available to project how each team's leading players will perform at Fiserv Forum.
CJ McCollum is expected to lead the Wizards in scoring, while Giannis Antetokounmpo is projected to be the top scorer for the Bucks.
Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.
Wizards vs. Bucks game-day updates and essential details
Wednesday's game between the Bucks and Wizards at Fiserv Forum is scheduled to start at 8:00PM ET.
- Who: Washington Wizards vs. Milwaukee Bucks
- Date: Wednesday, October 22, 2025
- Time: 8:00PM ET/5:00PM PT
- Venue: Fiserv Forum
Dimers' full preview of Wednesday's Wizards vs. Bucks matchup includes our prediction, picks and the latest betting odds.
Before making any Wizards vs. Bucks picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.
Conclusion
We predict the Bucks, with a 77% win probability, will likely beat the Wizards on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Wizards vs. Bucks insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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