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Wake Forest vs. Duke prediction: Duke favored to win men's college basketball matchup [1/24/2026]

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Written by Dave Garofolo

Get Wake Forest vs Duke predictions for college basketball Saturday.

Wake Forest-Duke Predictions and Game Preview.
Wake Forest vs. Duke men's college basketball prediction for Saturday, January 24, 2026.

Duke and Wake Forest will meet in men's college basketball action at Cameron Indoor Stadium on Saturday, with tipoff at 12:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts Duke as the most likely winner of the Wake Forest vs. Duke game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Wake Forest vs. Duke prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Saturday's NCAA basketball matchup between Wake Forest and Duke 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Duke a 94% chance of beating Wake Forest. Our predicted final score has Duke winning 86-67.

According to our model, Wake Forest (+19.5) has a 52% chance of covering the spread, while the over/under total of 153.5 points has a 55% chance of going over.

 

Wake Forest vs. Duke odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Wake Forest Duke
Spread +19.5 (-115) -19.5 (-102)
Moneyline +1280 -2400
Total o153.5 (-105) u153.5 (-110)

All odds are correct at the time of publication and are subject to change.

Wake Forest vs. Duke picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Wake Forest +19.5 -115
Moneyline Duke -2400
Total Over 153.5 -105

According to our men's college basketball best bets, the top play to make on this game is Over 153.5 total points.

 

Wake Forest vs. Duke game-day updates and essential details

Saturday's men's college basketball matchup between Duke and Wake Forest at Cameron Indoor Stadium is scheduled to begin at 12:00 PM ET.

  • Who: Wake Forest vs. Duke
  • Date: Saturday, January 24, 2026
  • Time: 12:00 PM ET/9:00AM PT
  • Venue: Cameron Indoor Stadium

Conclusion

We predict Duke, with a 94% win probability, will likely beat Wake Forest on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Wake Forest vs. Duke insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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