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Virginia vs. Louisville prediction: Louisville favored to win men's college basketball matchup [1/13/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Virginia vs Louisville predictions for college basketball Tuesday.
Louisville and Virginia will lock horns in men's college basketball action at KFC Yum! Center on Tuesday, starting at 7:00 PM ET.
Based on the latest simulation results, Dimers' proven college basketball model predicts Louisville as the most likely winner of the Virginia vs. Louisville game.
This article offers a closer look at Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
Virginia vs. Louisville prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the result of Tuesday's NCAA basketball matchup between Virginia and Louisville 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model currently gives Louisville a 69% chance of beating Virginia. Our predicted final score has Louisville winning 79-73.
According to our model, Louisville (-4.5) has a 55% chance of covering the spread, while the 154.5-point over/under has an equal 50-50 chance of hitting.
Virginia vs. Louisville odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Virginia | Louisville |
|---|---|---|
| Spread | +4.5 (-108) | -4.5 (-108) |
| Moneyline | +180 | -210 |
| Total | o154.5 (-110) | u154.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Virginia vs. Louisville picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Louisville -4.5 | -108 |
| Moneyline | Louisville | -210 |
| Total | Under 154.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Louisville -4.5 at the spread.
Virginia vs. Louisville game-day updates and essential details
Tuesday's men's college basketball matchup between Louisville and Virginia at KFC Yum! Center is scheduled to begin at 7:00 PM ET.
- Who: Virginia vs. Louisville
- Date: Tuesday, January 13, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: KFC Yum! Center
Conclusion
We predict Louisville, with a 69% win probability, will likely beat Virginia on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Virginia vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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