Villanova vs. Michigan prediction: Why Michigan is favored to win men's college basketball matchup [12/9/2025]

Michigan will face Villanova in men's college basketball action at Crisler Center on Tuesday, starting at 6:30PM ET.

Based on updated simulation results, Dimers' proven college basketball model predicts Michigan as the most likely winner of the Villanova vs. Michigan game.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

Villanova vs. Michigan prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Tuesday's NCAA basketball game between Villanova and Michigan 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Michigan a 91% chance of defeating Villanova. Our predicted final score has Michigan winning 84-69.

According to our model, Villanova (+15.5) has a 51% chance of covering the spread, while the over/under total of 150.5 points has a 53% chance of going over.

Villanova vs. Michigan odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Villanova vs. Michigan picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: