Villanova vs. Marquette prediction: Why Villanova is favored to win men's college basketball matchup [1/10/2026]

Marquette will square off with Villanova in men's college basketball action at Fiserv Forum on Saturday, starting at 2:30 PM ET.

Based on updated simulation results, Dimers' proven college basketball model predicts Villanova as the most likely winner of the Villanova vs. Marquette game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Villanova vs. Marquette prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the result of Saturday's NCAA basketball matchup between Villanova and Marquette 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Villanova a 61% chance of defeating Marquette. Our predicted final score has Villanova winning 73-71.

According to our model, Marquette (+3.5) has a 56% chance of covering the spread, while the over/under total of 145.5 points has a 52% chance of staying under.

Villanova vs. Marquette odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Villanova vs. Marquette picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: