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USC vs. Michigan State prediction: Why Michigan State is favored to win men's college basketball matchup [1/5/2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get USC vs Michigan State predictions for college basketball Monday.
Michigan State will square off with USC in men's college basketball action at Jack Breslin Students Events Center on Monday, starting at 8:30 PM ET.
Based on updated simulation results, Dimers' advanced college basketball model predicts Michigan State as the most likely winner of the USC vs. Michigan State game.
This article offers further insights into Monday's matchup, including an expanded look at the predicted score, best bets and picks.
USC vs. Michigan State prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Monday's NCAA basketball matchup between USC and Michigan State 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Michigan State an 87% chance of beating USC. Our predicted final score has Michigan State winning 82-70.
According to our model, Michigan State (-12.5) has a 56% chance of covering the spread, while the 151.5-point over/under has a 54% chance of going over.
USC vs. Michigan State odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | USC | Michigan State |
|---|---|---|
| Spread | +12.5 (-110) | -12.5 (-105) |
| Moneyline | +640 | -800 |
| Total | o151.5 (-105) | u151.5 (-115) |
All odds are correct at the time of publication and are subject to change.
USC vs. Michigan State picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Michigan State -12.5 | -105 |
| Moneyline | USC | +640 |
| Total | Over 151.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Michigan State -12.5 at the spread.
USC vs. Michigan State game-day updates and essential details
Monday's men's college basketball game between Michigan State and USC at Jack Breslin Students Events Center is scheduled to commence at 8:30 PM ET.
- Who: USC vs. Michigan State
- Date: Monday, January 5, 2026
- Time: 8:30 PM ET/5:30PM PT
- Venue: Jack Breslin Students Events Center
Conclusion
We predict Michigan State, with an 87% win probability, will likely beat USC on Monday.
AI and automation have enhanced this article to quickly deliver accurate USC vs. Michigan State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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