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USC vs. Iowa prediction: Why Iowa is favored to win men's college basketball matchup [1/28/2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get USC vs Iowa predictions for college basketball Wednesday.
Iowa will face USC in men's college basketball action at Carver-Hawkeye Arena on Wednesday, beginning at 7:00 PM ET.
Based on updated simulation results, Dimers' advanced college basketball model projects Iowa as the most likely winner of the USC vs. Iowa game.
This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
USC vs. Iowa prediction: Who will win and cover?
Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's NCAA basketball matchup between USC and Iowa 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Iowa an 82% chance of beating USC. Our predicted final score has Iowa winning 77-67.
According to our model, the bookmakers have got it right, and USC and Iowa each have a 50% chance of covering the spread, while the 141.5-point over/under has a 55% chance of going over.
USC vs. Iowa odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | USC | Iowa |
|---|---|---|
| Spread | +9.5 (-110) | -9.5 (-108) |
| Moneyline | +385 | -500 |
| Total | o141.5 (-108) | u141.5 (-110) |
All odds are correct at the time of publication and are subject to change.
USC vs. Iowa picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Iowa -9.5 | -108 |
| Moneyline | Iowa | -500 |
| Total | Over 141.5 | -108 |
According to our men's college basketball best bets, the top play to make on this game is Over 141.5 total points.
USC vs. Iowa game-day updates and essential details
Wednesday's men's college basketball action between Iowa and USC at Carver-Hawkeye Arena is scheduled to start at 7:00 PM ET.
- Who: USC vs. Iowa
- Date: Wednesday, January 28, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: Carver-Hawkeye Arena
Conclusion
We predict Iowa, with an 82% win probability, will likely beat USC on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate USC vs. Iowa insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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