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USC vs. Arizona State prediction: Why USC is favored to win men's college basketball matchup [11/26/2025]

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Written by Mac Douglass

Get USC vs Arizona State predictions for college basketball Wednesday.

USC-Arizona State Predictions and Game Preview.
USC vs. Arizona State men's college basketball prediction for Wednesday, November 26, 2025.

Arizona State will face the favored USC in men's college basketball action at Lahaina Civic Center on Wednesday, starting at 2:30PM ET.

Based on the latest simulations, Dimers' proven college basketball model predicts USC as the most likely winner of the USC vs. Arizona State game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

USC vs. Arizona State prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Wednesday's NCAA basketball game between USC and Arizona State 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives USC a 67% chance of beating Arizona State. Our predicted final score has USC winning 81-76.

According to our model, Arizona State (+5.5) has a 55% chance of covering the spread, while the 164.5-point over/under has a 55% chance of staying under.

 

USC vs. Arizona State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type USC Arizona State
Spread -5.5 (-106) +5.5 (-110)
Moneyline -235 +190
Total o164.5 (-105) u164.5 (-110)

All odds are correct at the time of publication and are subject to change.

USC vs. Arizona State picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Arizona State +5.5 -110
Moneyline Arizona State +190
Total Under 164.5 -110

According to our men's college basketball best bets, the top play to make on this game is Arizona State +5.5 at the spread.

 

USC vs. Arizona State game-day updates and essential details

Wednesday's men's college basketball game between Arizona State and USC at Lahaina Civic Center is scheduled to start at 2:30PM ET.

  • Who: USC vs. Arizona State
  • Date: Wednesday, November 26, 2025
  • Time: 2:30PM ET/11:30AM PT
  • Venue: Lahaina Civic Center

 

Conclusion

We predict USC, with a 67% win probability, will likely beat Arizona State on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate USC vs. Arizona State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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