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USC Upstate vs. Kentucky prediction: Kentucky favored to win women's college basketball matchup [11/12/2025]

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Written by Ryan Leaver

Get USC Upstate vs Kentucky predictions for college basketball Wednesday.

USC Upstate-Kentucky Predictions and Game Preview.
USC Upstate vs. Kentucky women's college basketball prediction for Wednesday, November 12, 2025.

Kentucky will face USC Upstate in women's college basketball action at Memorial Coliseum on Wednesday, starting at 6:30PM ET.

Based on the latest simulation results, Dimers' new women's basketball model projects Kentucky as the most likely winner of the USC Upstate vs. Kentucky game.

This article offers further insights into Wednesday's matchup, including best bets and picks.

USC Upstate vs. Kentucky prediction: Who will win?

Using innovative machine learning and data analysis, we have simulated the result of Wednesday's women's basketball matchup between USC Upstate and Kentucky 10,000 times as part of our women's college basketball predictions coverage.

Our leading predictive model currently gives Kentucky a 99% chance of beating USC Upstate.

According to our model, the 133.5-point over/under has a 59% chance of staying under.

 

USC Upstate vs. Kentucky odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

Bet Type USC Upstate Kentucky
Spread +52.5 (-105) -52.5 (-114)
Total o133.5 (-110) u133.5 (-110)

All odds are correct at the time of publication and are subject to change.

USC Upstate vs. Kentucky picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread USC Upstate +52.5 -105
Total Under 133.5 -110

According to our best women's college basketball bets, the top play to make on this game is under 133.5 points.

 

USC Upstate vs. Kentucky game-day updates and essential details

Wednesday's women's basketball game between Kentucky and USC Upstate at Memorial Coliseum is scheduled to start at 6:30PM ET.

  • Who: USC Upstate vs. Kentucky
  • Date: Wednesday, November 12, 2025
  • Time: 6:30PM ET/3:30PM PT
  • Venue: Memorial Coliseum

Conclusion

We predict Kentucky, with a 99% win probability, will likely beat USC Upstate on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate USC Upstate vs. Kentucky insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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