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USC Upstate vs. Charleston Southern prediction: Why Charleston Southern is favored to win men's college basketball matchup [1/14/2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get USC Upstate vs Charleston Southern predictions for college basketball Wednesday.
Charleston Southern and USC Upstate are scheduled to meet in men's college basketball action at The Buc Dome on Wednesday, starting at 7:00 PM ET.
Based on the latest simulation results, Dimers' advanced college basketball model predicts Charleston Southern as the most likely winner of the USC Upstate vs. Charleston Southern game.
This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
USC Upstate vs. Charleston Southern prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the result of Wednesday's NCAA basketball game between USC Upstate and Charleston Southern 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Charleston Southern a 74% chance of defeating USC Upstate. Our predicted final score has Charleston Southern winning 82-75.
According to our model, Charleston Southern (-6.5) has a 55% chance of covering the spread, while the 155.5-point over/under has a 52% chance of going over.
USC Upstate vs. Charleston Southern odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | USC Upstate | Charleston Southern |
|---|---|---|
| Spread | +6.5 (-110) | -6.5 (-104) |
| Moneyline | +220 | -265 |
| Total | o155.5 (-112) | u155.5 (-105) |
All odds are correct at the time of publication and are subject to change.
USC Upstate vs. Charleston Southern picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Charleston Southern -6.5 | -104 |
| Moneyline | Charleston Southern | -265 |
| Total | Over 155.5 | -112 |
According to our men's college basketball best bets, the top play to make on this game is Charleston Southern -6.5 at the spread.
USC Upstate vs. Charleston Southern game-day updates and essential details
Wednesday's men's college basketball action between Charleston Southern and USC Upstate at The Buc Dome is scheduled to start at 7:00 PM ET.
- Who: USC Upstate vs. Charleston Southern
- Date: Wednesday, January 14, 2026
- Time: 7:00 PM ET/4:00PM PT
- Venue: The Buc Dome
Conclusion
We predict Charleston Southern, with a 74% win probability, will likely beat USC Upstate on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate USC Upstate vs. Charleston Southern insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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