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Maple Leafs vs. Panthers Prediction: Florida Predicted to Win Friday's NHL Matchup [5/16/2025]

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Written by Nick Slade

Our expert prediction for Friday's Toronto Maple Leafs vs Florida Panthers matchup.

Toronto Maple Leafs-Florida Panthers Predictions and Game Preview.
Amerant Bank Arena sets the stage for the NHL matchup between the Toronto Maple Leafs and Florida Panthers this Friday.

NHL action continues on Friday at 8:00PM ET as the Toronto Maple Leafs lock horns with the Florida Panthers in Game 225 of the 2025 Conference Final at Amerant Bank Arena.

Based on the latest simulations, Dimers' advanced NHL model (see Dimers Pro for full access) predicts the Panthers as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Toronto-Florida game 10,000 times," said Mac Douglass from Dimers.

"After computing the latest updates and thousands of other inputs, we predict the Panthers' chance of winning is 62%, while the Maple Leafs' is 38%."

For a closer look at Friday's matchup, including best bets and player prop picks, visit our interactive Maple Leafs vs. Panthers predictions page.

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Panthers vs. Maple Leafs Prediction: Who Will Win, Cover the Puck Line?

Using innovative machine learning and statistical analysis, we have simulated the result of Friday's NHL Playoffs matchup between the Maple Leafs and Panthers 10,000 times as part of our NHL predictions coverage.

Our leading predictive model gives the Panthers a 62% chance of defeating the Maple Leafs in Game 225 of the 2025 Conference Finals.

According to our model, the Maple Leafs (+1.5) have a 61% chance of covering the puck line, while the 5.5-goal over/under has a 52% chance of going over.

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Maple Leafs vs. Panthers Game 225 Odds

We have sourced the best NHL odds in America for this game, which are listed here:

Bet Type Maple Leafs Panthers
Puck Line +1.5 (-135) -1.5 (+126)
Moneyline +180 -200
Total o5.5 (-110) u5.5 (+100)

All odds are correct at the time of publication and are subject to change.

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Maple Leafs vs. Panthers Picks and Best Bets

Our model's strongest edge in today's Maple Leafs vs. Panthers matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best NHL picks and NHL best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Maple Leafs vs. Panthers Player Props

Who will score the first goal in Maple Leafs vs. Panthers?

According to our model, Toronto's Auston Matthews is most likely to score the first goal in Maple Leafs vs. Panthers.

Our projections give Matthews a 7.7% chance of scoring the first goal at Amerant Bank Arena, while the Maple Leafs star is a 37.2% chance of registering an anytime goal.

First Goal Scorer Predictions

Toronto Maple Leafs

Player First Goal Probability
Auston Matthews 7.7%
William Nylander 6.4%
John Tavares 5.2%

Florida Panthers

Player First Goal Probability
Carter Verhaeghe 7.6%
Sam Reinhart 7.4%
Matthew Tkachuk 5.8%

Anytime Goal Scorer Predictions

Toronto Maple Leafs

Player Anytime Goal Probability
Auston Matthews 37.2%
William Nylander 29.6%
John Tavares 28.0%

Florida Panthers

Player Anytime Goal Probability
Sam Reinhart 35.8%
Carter Verhaeghe 34.7%
Matthew Tkachuk 27.7%

Maple Leafs vs. Panthers Game-Day Updates and Essential Details

Friday's game between the Panthers and Maple Leafs in the Stanley Cup Playoffs is scheduled to commence at 8:00PM ET.

The winner of the NHL Conference Final will advance to the Stanley Cup Final. Game 225 of the best-of-seven series between the Maple Leafs and Panthers is at Florida's Amerant Bank Arena.

Dimers.com's comprehensive preview of Friday's Maple Leafs vs. Panthers matchup includes our prediction, picks and the latest betting odds.

Before making any Toronto vs. Florida picks, be sure to check out the latest NHL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Panthers, with a 62% win probability, will likely beat the Maple Leafs in Game 225 of the 2025 Conference Finals.

AI and automation have enhanced this article to quickly deliver accurate Maple Leafs vs. Panthers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NHL

Stay up-to-date with the latest NHL betting news and parlay picks throughout the season. Plus, our Stanley Cup odds offer the most up-to-date projections for the Stanley Cup title.

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Written by
Nick Slade
Chief Content Officer

Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.

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