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Toledo vs. Michigan State prediction: Why Michigan State is favored to win men's college basketball matchup [12/16/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Toledo vs Michigan State predictions for college basketball Tuesday.
Men's college basketball action continues on Tuesday at 6:30 PM ET as Toledo faces off with the favored Michigan State in men's college basketball action at Jack Breslin Students Events Center.
Based on the latest simulation results, Dimers' proven college basketball model predicts Michigan State as the most likely winner of the Toledo vs. Michigan State game.
This article offers an expanded analysis of Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
Toledo vs. Michigan State prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Tuesday's NCAA basketball matchup between Toledo and Michigan State 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Michigan State a 97% chance of defeating Toledo. Our predicted final score has Michigan State winning 87-64.
According to our model, Michigan State (-22.5) has a 51% chance of covering the spread, while the over/under total of 150.5 points has a 52% chance of staying under.
Toledo vs. Michigan State odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Toledo | Michigan State |
|---|---|---|
| Spread | +22.5 (-102) | -22.5 (-115) |
| Moneyline | +2200 | -6502 |
| Total | o150.5 (-115) | u150.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Toledo vs. Michigan State picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Toledo +22.5 | -102 |
| Moneyline | Michigan State | -6502 |
| Total | Under 150.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Under 150.5 total points.
Toledo vs. Michigan State game-day updates and essential details
Tuesday's men's college basketball matchup between Michigan State and Toledo at Jack Breslin Students Events Center is scheduled to commence at 6:30 PM ET.
- Who: Toledo vs. Michigan State
- Date: Tuesday, December 16, 2025
- Time: 6:30 PM ET/3:30PM PT
- Venue: Jack Breslin Students Events Center
Conclusion
We predict Michigan State, with a 97% win probability, will likely beat Toledo on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Toledo vs. Michigan State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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