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Tennessee vs. Louisville prediction: Tennessee favored to win women's college basketball matchup [12/20/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Tennessee vs Louisville predictions for college basketball Saturday.
Women's college basketball action continues on Saturday at 11:00 AM ET as Tennessee takes on Louisville at Barclays Center.
Based on updated simulations, Dimers' new women's basketball model projects Tennessee as the most likely winner of the Tennessee vs. Louisville game.
This article offers further insights into Saturday's matchup, including best bets and picks.
Tennessee vs. Louisville prediction: Who will win?
Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's women's basketball matchup between Tennessee and Louisville 10,000 times as part of our women's college basketball predictions coverage.
Our leading predictive model gives Tennessee a 63% chance of defeating Louisville.
According to our model, the over/under total of 148.5 points has a 52% chance of going over.
Tennessee vs. Louisville odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Tennessee | Louisville |
|---|---|---|
| Spread | +1.5 (-110) | -1.5 (-110) |
| Moneyline | +100 | -105 |
| Total | o148.5 (-112) | u148.5 (-118) |
All odds are correct at the time of publication and are subject to change.
Tennessee vs. Louisville picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Tennessee +1.5 | -110 |
| Moneyline | Tennessee | +100 |
| Total | Over 148.5 | -112 |
According to our women's college basketball best bets, the top play to make on this game is Tennessee to win.
Tennessee vs. Louisville game-day updates and essential details
Saturday's women's basketball matchup between Louisville and Tennessee at Barclays Center is scheduled to start at 11:00 AM ET.
- Who: Tennessee vs. Louisville
- Date: Saturday, December 20, 2025
- Time: 11:00 AM ET/8:00AM PT
- Venue: Barclays Center
Conclusion
We predict Tennessee, with a 63% win probability, will likely beat Louisville on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Tennessee vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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