College Basketball- More Betting
Syracuse vs. SMU Prediction: SMU Predicted to Win College Basketball Matchup [3/12/2025]
Our expert prediction for Wednesday's Syracuse vs SMU matchup.

SMU and Syracuse will meet in college basketball action at Spectrum Center on Wednesday, starting at 9:30PM ET.
Based on the latest simulation results, Dimers' advanced college basketball model (see Dimers Pro for full access) projects SMU as the most likely winner of today's game.
Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities.
"Our team has simulated the outcome of Wednesday's Syracuse-SMU game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.
"With the latest updates and numerous other variables, we estimate SMU's chance of winning at 78%, with Syracuse at 22%."
For expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Syracuse vs. SMU predictions page.
READER EXCLUSIVE: Use code 20BASKETBALL at checkout now to get 20% off your first month of Dimers Pro! Hurry, this offer won't last long.
Syracuse vs. SMU Prediction: Who Will Win, Cover the Spread?
Using powerful machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball game between Syracuse and SMU 10,000 times as part of our college basketball predictions coverage.
Our independent predictive model currently gives SMU a 78% chance of defeating Syracuse. Our predicted final score has SMU winning 80-71.
According to our model, the bookmakers have got it right, and Syracuse and SMU each have a 50% chance of covering the spread, while the 150.5-point over/under has a 53% chance of going over.
Syracuse vs. SMU Odds
We have researched the best College Basketball odds in America for this game, which are listed here:
Bet Type | Syracuse | SMU |
---|---|---|
Spread | +8.5 (-105) | -8.5 (-115) |
Moneyline | +350 | -410 |
Total | o150.5 (-105) | u150.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.
Syracuse vs. SMU Picks and Best Bets
Our model's biggest edge in today's Syracuse vs. SMU matchup is on the spread.
Our expert predictions, aligned with the latest odds, reveal the best college basketball picks for every game throughout the season.
Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.
Syracuse vs. SMU Game-Day Updates and Essential Details
Wednesday's college basketball action between SMU and Syracuse at Spectrum Center is scheduled to commence at 9:30PM ET.
- Who: Syracuse vs. SMU
- Date: Wednesday, March 12, 2025
- Time: 9:30PM ET/6:30PM PT
- Venue: Spectrum Center
Dimers.com's comprehensive preview of Wednesday's Syracuse vs. SMU matchup includes our prediction, picks and the latest betting odds.
Before making any Syracuse vs. SMU picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.
Conclusion
We predict SMU, with a 78% win probability, will likely beat Syracuse on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Syracuse vs. SMU insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
More on College Basketball
Keep up with the latest college basketball news, college basketball best bets and CBB parlay picks throughout the season. Plus, our odds offer the most up-to-date projections for every March Madness contender.