Syracuse vs. Pittsburgh prediction: Why Pittsburgh is favored to win men's college basketball matchup [1/10/2026]

Pittsburgh will face Syracuse in men's college basketball action at Petersen Events Center on Saturday, commencing at 2:00 PM ET.

Based on updated simulations, Dimers' advanced college basketball model predicts Pittsburgh as the most likely winner of the Syracuse vs. Pittsburgh game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Syracuse vs. Pittsburgh prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Syracuse and Pittsburgh 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Pittsburgh a 56% chance of defeating Syracuse. Our predicted final score has Pittsburgh winning 72-70.

According to our model, the bookmakers have got it right, and Syracuse and Pittsburgh each have a 50% chance of covering the spread, while the over/under total of 142.5 points has a 52% chance of going over.

Syracuse vs. Pittsburgh odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Syracuse vs. Pittsburgh picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: