Cardinals vs. Dodgers Prediction: Dodgers Predicted to Win Wednesday's MLB Matchup [8/6/2025]

The Los Angeles Dodgers will face the St. Louis Cardinals in MLB action at Dodger Stadium on Wednesday, starting at 4:10PM ET.

The Dodgers will start Shohei Ohtani (0-0, 2.40 ERA), pitting him against Matthew Liberatore (6-9, 3.96 ERA) for the Cardinals.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Dodgers as the most likely winner of today's game. "Our team has simulated the outcome of Wednesday's Cardinals-Dodgers game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Dodgers' chance of winning at 65%, with the Cardinals at 35%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Cardinals vs. Dodgers predictions page.

Dodgers vs. Cardinals Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB matchup between the Cardinals and Dodgers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Dodgers a 65% chance of beating the Cardinals.

According to our model, the Cardinals (+1.5) have a 53% chance of covering the run line, while the 9.5-run over/under has a 53% chance of staying under.

Cardinals vs. Dodgers Odds [8/6/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Cardinals	Dodgers
Run Line	+1.5 (-103)	-1.5 (-110)
Moneyline	+180	-215
Total	o9.5 (-102)	u9.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Cardinals vs. Dodgers Picks and Best Bets

Our model's strongest edge in today's Cardinals vs. Dodgers matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Cardinals vs. Dodgers Game-Day Updates and Essential Details

Wednesday's MLB matchup between the Dodgers and Cardinals at Dodger Stadium is scheduled to commence at 4:10PM ET.

• Who: St. Louis Cardinals vs. Los Angeles Dodgers
• Date: Wednesday, August 6, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: Dodger Stadium

Dimers.com's comprehensive preview of Wednesday's Cardinals vs. Dodgers matchup includes our prediction, picks and the latest betting odds.

Before making any Cardinals vs. Dodgers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Dodgers, with a 65% win probability, will likely beat the Cardinals on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Dodgers insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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