St. John's vs. Villanova prediction: St. John's favored to win men's college basketball matchup [1/17/2026]

Men's college basketball action continues on Saturday at 8:00 PM ET as St. John's takes on Villanova in men's college basketball action at Xfinity Mobile Arena.

Based on updated simulations, Dimers' advanced college basketball model predicts St. John's as the most likely winner of the St. John's vs. Villanova game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

St. John's vs. Villanova prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Saturday's NCAA basketball matchup between St. John's and Villanova 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives St. John's a 60% chance of defeating Villanova. Our predicted final score has St. John's winning 75-72.

According to our model, Villanova (+3.5) has a 56% chance of covering the spread, while the 148.5-point over/under has a 55% chance of staying under.

St. John's vs. Villanova odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

St. John's vs. Villanova picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: