St. John's vs. Marquette prediction: Why St. John's is favored to win men's college basketball matchup [2/18/2026]

Men's college basketball action continues on Wednesday at 9:00 PM ET as the favored St. John's squares off with Marquette in men's college basketball action at Fiserv Forum.

Based on updated simulation results, Dimers' advanced college basketball model predicts St. John's as the most likely winner of the St. John's vs. Marquette game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

St. John's vs. Marquette prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball matchup between St. John's and Marquette 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives St. John's a 77% chance of defeating Marquette. Our predicted final score has St. John's winning 80-72.

According to our model, Marquette (+8.5) has a 51% chance of covering the spread, while the over/under total of 157.5 points has a 54% chance of staying under.

St. John's vs. Marquette odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

St. John's vs. Marquette picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: