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St. John's vs. DePaul prediction: St. John's favored to win men's college basketball matchup [2/3/2026]

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Written by Dave Garofolo

Get St. John's vs DePaul predictions for college basketball Tuesday.

St. John's-DePaul Predictions and Game Preview.
St. John's vs. DePaul men's college basketball prediction for Tuesday, February 3, 2026.

DePaul will face the favored St. John's in men's college basketball action at Wintrust Arena on Tuesday, commencing at 8:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts St. John's as the most likely winner of the St. John's vs. DePaul game.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

St. John's vs. DePaul prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Tuesday's NCAA basketball matchup between St. John's and DePaul 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives St. John's an 80% chance of defeating DePaul. Our predicted final score has St. John's winning 77-68.

According to our model, DePaul (+9.5) has a 55% chance of covering the spread, while the over/under total of 145.5 points has an equal 50-50 chance of hitting.

 

St. John's vs. DePaul odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type St. John's DePaul
Spread -9.5 (-102) +9.5 (-112)
Moneyline -450 +380
Total o145.5 (-105) u145.5 (-110)

All odds are correct at the time of publication and are subject to change.

St. John's vs. DePaul picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread DePaul +9.5 -112
Moneyline DePaul +380
Total Over 145.5 -105

According to our men's college basketball best bets, the top play to make on this game is DePaul +9.5 at the spread.

 

St. John's vs. DePaul game-day updates and essential details

Tuesday's men's college basketball game between DePaul and St. John's at Wintrust Arena is scheduled to start at 8:00 PM ET.

  • Who: St. John's vs. DePaul
  • Date: Tuesday, February 3, 2026
  • Time: 8:00 PM ET/5:00PM PT
  • Venue: Wintrust Arena

Conclusion

We predict St. John's, with an 80% win probability, will likely beat DePaul on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate St. John's vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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