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Southern Miss vs. North Florida prediction: Southern Miss favored to win men's college basketball matchup [11/22/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Southern Miss vs North Florida predictions for college basketball Saturday.
North Florida will square off with the favored Southern Miss in men's college basketball action at Pensacola Bay Center on Saturday, beginning at 8:00PM ET.
Based on updated simulations, Dimers' advanced college basketball model projects Southern Miss as the most likely winner of the Southern Miss vs. North Florida game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Southern Miss vs. North Florida prediction: Who will win and cover?
Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball game between Southern Miss and North Florida 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model gives Southern Miss a 79% chance of defeating North Florida. Our predicted final score has Southern Miss winning 82-73.
According to our model, North Florida (+9.5) has a 55% chance of covering the spread, while the over/under total of 154.5 points has a 52% chance of going over.
Southern Miss vs. North Florida odds
We have sourced the best Men's College Basketball odds in America for this game, which are listed here:
| Bet Type | Southern Miss | North Florida |
|---|---|---|
| Spread | -9.5 (-105) | +9.5 (-110) |
| Moneyline | -475 | +425 |
| Total | o154.5 (-105) | u154.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Southern Miss vs. North Florida picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | North Florida +9.5 | -110 |
| Moneyline | North Florida | +425 |
| Total | Over 154.5 | -105 |
According to our best men's college basketball bets, the top play to make on this game is North Florida +9.5 at the spread.
Southern Miss vs. North Florida game-day updates and essential details
Saturday's men's college basketball matchup between North Florida and Southern Miss at Pensacola Bay Center is scheduled to start at 8:00PM ET.
- Who: Southern Miss vs. North Florida
- Date: Saturday, November 22, 2025
- Time: 8:00PM ET/5:00PM PT
- Venue: Pensacola Bay Center
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Conclusion
We predict Southern Miss, with a 79% win probability, will likely beat North Florida on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Southern Miss vs. North Florida insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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