Southern Miss vs. Marshall prediction: Why Marshall is favored to win men's college basketball matchup [2/4/2026]

Marshall and Southern Miss will meet in men's college basketball action at Cam Henderson Center on Wednesday, starting at 7:00 PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts Marshall as the most likely winner of the Southern Miss vs. Marshall game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Southern Miss vs. Marshall prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's NCAA basketball game between Southern Miss and Marshall 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Marshall an 85% chance of beating Southern Miss. Our predicted final score has Marshall winning 79-68.

According to our model, Marshall (-9.5) has a 51% chance of covering the spread, while the over/under total of 148.5 points has a 52% chance of staying under.

Southern Miss vs. Marshall odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Southern Miss vs. Marshall picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Marshall to win.

Southern Miss vs. Marshall game-day updates and essential details

Wednesday's men's college basketball action between Marshall and Southern Miss at Cam Henderson Center is scheduled to begin at 7:00 PM ET.

• Who: Southern Miss vs. Marshall
• Date: Wednesday, February 4, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: Cam Henderson Center

Conclusion

We predict Marshall, with an 85% win probability, will likely beat Southern Miss on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Southern Miss vs. Marshall insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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