Southeast Missouri State vs. Southern Indiana prediction: Southeast Missouri State favored to win men's college basketball matchup [1/8/2026]

Men's college basketball action continues on Thursday at 8:30 PM ET as the favored Southeast Missouri State squares off with Southern Indiana in men's college basketball action at Liberty Arena.

Based on the latest simulation results, Dimers' proven college basketball model projects Southeast Missouri State as the most likely winner of the Southeast Missouri State vs. Southern Indiana game.

This article offers an expanded analysis of Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

Southeast Missouri State vs. Southern Indiana prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Thursday's NCAA basketball game between Southeast Missouri State and Southern Indiana 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Southeast Missouri State a 78% chance of defeating Southern Indiana. Our predicted final score has Southeast Missouri State winning 77-69.

According to our model, Southeast Missouri State (-7.5) has a 55% chance of covering the spread, while the 146.5-point over/under has a 52% chance of going over.

Southeast Missouri State vs. Southern Indiana odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Southeast Missouri State vs. Southern Indiana picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: