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Southeast Missouri State vs. Saint Louis prediction: Saint Louis favored to win men's college basketball matchup [11/3/2025]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Southeast Missouri State vs Saint Louis predictions for college basketball Monday.
Saint Louis and Southeast Missouri State will lock horns in men's college basketball opening night action at Chaifetz Arena on Monday, with tipoff at 8:00PM ET.
Based on updated simulation results, Dimers' proven college basketball model projects the Saint Louis as the most likely winner of the Southeast Missouri State vs. Saint Louis game.
This article offers further insights into Monday's matchup, including an expanded look at the predicted score, best bets and picks.
Southeast Missouri State vs. Saint Louis prediction: Who will win, cover the spread?
Using innovative machine learning and data, we have simulated the outcome of Monday's NCAA basketball game between Southeast Missouri State and Saint Louis 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Saint Louis a 95% chance of beating Southeast Missouri State. Our predicted final score has Saint Louis winning 85-66.
According to our model, Saint Louis (-18.5) has a 51% chance of covering the spread, while the 153.5-point over/under has an equal 50-50 chance of hitting.
Southeast Missouri State vs. Saint Louis odds
We have sourced the best college basketball odds in America for this game, which are listed here:
| Bet Type | Southeast Missouri State | Saint Louis |
|---|---|---|
| Spread | +18.5 (-105) | -18.5 (-115) |
| Moneyline | +1260 | -2400 |
| Total | o153.5 (-105) | u153.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Southeast Missouri State vs. Saint Louis picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Southeast Missouri State +18.5 | -105 |
| Moneyline | Saint Louis | -2400 |
| Total | Over 153.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Saint Louis to win.
Southeast Missouri State vs. Saint Louis game-day updates and essential details
Monday's men's college basketball matchup between Saint Louis and Southeast Missouri State at Chaifetz Arena is scheduled to start at 8:00PM ET.
- Who: Southeast Missouri State vs. Saint Louis
- Date: Monday, November 3, 2025
- Time: 8:00PM ET/5:00PM PT
- Venue: Chaifetz Arena
Conclusion
We predict Saint Louis, with a 95% win probability, will likely beat Southeast Missouri State on Monday.
AI and automation have enhanced this article to quickly deliver accurate Southeast Missouri State vs. Saint Louis insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on men's college basketball
Keep up with the latest men's college basketball betting news and CBB parlay picks throughout the season. Plus, our NCAA Tournament Championship odds offer the latest projections for every March Madness contender.
Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.
Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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