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Southeast Missouri State vs. Cal Poly prediction: Why Cal Poly is favored to win men's college basketball matchup [11/25/2025]

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Written by Dave Garofolo

Get Southeast Missouri State vs Cal Poly predictions for college basketball Tuesday.

Southeast Missouri State-Cal Poly Predictions and Game Preview.
Southeast Missouri State vs. Cal Poly men's college basketball prediction for Tuesday, November 25, 2025.

Cal Poly will face Southeast Missouri State, in what is expected to be a close Men's College Basketball game, at J. Lawrence Walkup Skydome on Tuesday, starting at 8:00PM ET.

Based on the latest simulation results, Dimers' proven college basketball model gives Cal Poly a slight edge with a 51% win probability over Southeast Missouri State.

This article offers a closer look at Tuesday's Southeast Missouri State vs. Cal Poly matchup, including an expanded look at the predicted score, best bets and picks.

Southeast Missouri State vs. Cal Poly prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Tuesday's NCAA basketball matchup between Southeast Missouri State and Cal Poly 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Cal Poly a 51% chance of beating Southeast Missouri State. Our predicted score is Southeast Missouri State 81-81 Cal Poly.

According to our model, Cal Poly (+1.5) has a 55% chance of covering the spread, while the over/under total of 169.5 points has a 54% chance of staying under.

While there is no way for a men's college basketball game to end in a tie, our prediction of 81-81 is based on each team's average score in the above-mentioned simulations of Southeast Missouri State vs. Cal Poly.

 

Southeast Missouri State vs. Cal Poly odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Southeast Missouri State Cal Poly
Spread -1.5 (-106) +1.5 (-112)
Moneyline -122 +102
Total o169.5 (-114) u169.5 (-106)

All odds are correct at the time of publication and are subject to change.

Southeast Missouri State vs. Cal Poly picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Cal Poly +1.5 -112
Moneyline Cal Poly +102
Total Under 169.5 -106

According to our men's college basketball best bets, the top play to make on this game is Under 169.5 total points.

 

Southeast Missouri State vs. Cal Poly game-day updates and essential details

Tuesday's men's college basketball action between Cal Poly and Southeast Missouri State at J. Lawrence Walkup Skydome is scheduled to commence at 8:00PM ET.

  • Who: Southeast Missouri State vs. Cal Poly
  • Date: Tuesday, November 25, 2025
  • Time: 8:00PM ET/5:00PM PT
  • Venue: J. Lawrence Walkup Skydome

 

Conclusion

We predict Cal Poly, with a 51% win probability, will likely beat Southeast Missouri State on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Southeast Missouri State vs. Cal Poly insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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